DRSC/TRiP Functional Genomics Resources

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Protein Alignment RhoGAP54D and arhgap19

DIOPT Version :10

Sequence 1:NP_611236.2 Gene:RhoGAP54D / 36996 FlyBaseID:FBgn0034249 Length:1004 Species:Drosophila melanogaster
Sequence 2:XP_003201186.1 Gene:arhgap19 / 100537002 ZFINID:ZDB-GENE-100922-157 Length:454 Species:Danio rerio


Alignment Length:445 Identity:133/445 - (29%)
Similarity:202/445 - (45%) Gaps:56/445 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly    23 RMRRCNYEKYKSLVRMHLSFELELNTDEFD--LPCHEIVYEDKGKLKKWNRLSKKHRLGHGAAAT 85
            :||....|.:..||..:::..::|...||.  |...|....:.|..:.:|.|.:|          
Zfish    49 KMRHERPEAFTELVLSNITRLIDLPGAEFSQLLGDEEPKTPNAGFFRSFNFLKRK---------- 103

  Fly    86 SCAAGSASKSV--GNSPTETLQQQIDPGFLMHLQELKEFLMLEKNLTQEGLFRKAGAVSRQNELR 148
                   .|.|  |...||....||          .:....|.|||..:||||..|...||..||
Zfish   104 -------DKGVVFGMPLTEEGIAQI----------YQLIAYLSKNLHVQGLFRVPGNSLRQQTLR 151

  Fly   149 MHIQHDKPLNLELAGFSAHDCATVFKGFLSELPEPLLTDAHYPAHLQIAPLCQALN-GQTTATAE 212
            ..:.....::.....|..:|.||:.|.||.||||||||..|..|||:|..|....: |..|:..:
Zfish   152 EQLNSGADIDFAAGDFHPNDVATLLKSFLGELPEPLLTHRHLHAHLKITELTTFDDEGNKTSFPD 216

  Fly   213 RQQHLLNSVQLLLLLLPEEHRELLQHIIEMLHAVAKHEKSNKMSADNLATLFTPHLICPRQLPPE 277
            :::. :.::||||||||..:|.||:.::::|:..||.:..|||||.|||.:|.||:|.|:.:...
Zfish   217 KERQ-IEALQLLLLLLPTANRTLLKLLLDLLYHTAKQQDKNKMSAHNLALMFGPHVIWPKNMNAS 280

  Fly   278 VLHYQAKKMSSIVTYMIVRGLDIFEVPGKLSTDIRAYFLERKRKKTMSPEQTLDESISDVSTVNT 342
            .|....||::|.:.::|.....||..|..|....|..|...|..::....:.|  |:|....::.
Zfish   281 DLQENLKKLNSGMAFLIKHSQKIFRAPAYLREHARLQFANTKILQSKDDLELL--SVSGSPFISA 343

  Fly   343 VYTFVDRAATAAATNTNNTDTELAQLYAHI-QSMPESSKKRRLIKQFNKQNGQGTPLQLVVMNRL 406
            .....:|   ....:.|:|:..|.:||.|: .:||.|:||::||:|..|.:..|||:        
Zfish   344 CKRSGER---VRLDSDNHTEEALKELYRHVTDNMPNSAKKKKLIRQLGKPSTPGTPV-------- 397

  Fly   407 KNNEATRSAK------SLGDSIKKHIFHKSLMSRTPKRVPPSFHLASGSETPNMS 455
             |...|.|:|      |.|..||:.:.......|..:.|.|......|.|  |:|
Zfish   398 -NENLTPSSKKHGRSRSFGGLIKRKVLGGQPADRRGRHVSPQSAAGLGKE--NIS 449

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RhoGAP54DNP_611236.2 RhoGAP 107..313 CDD:470621 74/206 (36%)
arhgap19XP_003201186.1 RhoGAP_ARHGAP19 109..316 CDD:239857 77/217 (35%)

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