Protein Alignment RhoGAP54D and arhgap19

DIOPT Version :9

• Sequence 1: NP_001261060.1
• Gene: RhoGAP54D / 36996
• FlyBaseID: FBgn0034249
• Length: 1004
• Species: Drosophila melanogaster
• Sequence 2: XP_002939704.1
• Gene: arhgap19 / 100497228
• XenbaseID: XB-GENE-6041529
• Length: 507
• Species: Xenopus tropicalis
• Alignment Length: 568
• Identity: 162/568 - (28%)
• Similarity: 252/568 - (44%)
• Gaps: 118/568 - (20%)

  Fly     1 MEATMD---TDHANLND-------FRDRDLAT------------RMRRCNYEKYKSLVRMHLSFE 43
            |.||.|   :|..|..|       ..|..|.:            ::|..|.|.:..||..:|:..
 Frog     1 MAATEDGGESDRGNSGDALCRIVICNDASLRSQPVIYNPDFFVEKLRHENTEVFTELVVSNLTRL 65

  Fly    44 LELNTDEFDLPCHEIVYEDKGKL-----------KKWNRLSKKHR-LGHGAAATSCAAGSASKSV 96
            ::|...||    .:::.|...||           :..|.|.:|.: :..||..|.  .|.|.
 Frog    66 IDLPGTEF----AQLMGEVDPKLPSNNGAASSFFRSLNFLKRKEKGIVFGAPLTE--EGIAQ--- 121

  Fly    97 GNSPTETLQQQIDPGFLMHLQELKEFLMLEKNLTQEGLFRKAGAVSRQNELRMHIQHDKPLNLEL 161
                   :.|.||              .|.|||..|||||..|..:||..|:..:.....:::|.
 Frog   122 -------IYQLID--------------YLHKNLRTEGLFRIPGNSNRQQILKDLLNSGMDIDVES 165

  Fly   162 AGFSAHDCATVFKGFLSELPEPLLTDAHYPAHLQIAPLC--QALNGQTTATAERQQHLLNSVQLL 224
            ..|..:|.||:.|.:|.||||||||..||.:||:||.|.  .|...:|.|..:.:|  :.::|||
 Frog   166 GEFHPNDVATLLKMYLGELPEPLLTHRHYNSHLKIANLMLFDAKGNRTGAPDKERQ--IEALQLL 228

  Fly   225 LLLLPEEHRELLQHIIEMLHAVAKHEKSNKMSADNLATLFTPHLICPRQLPPEVLHYQAKKMSSI 289
            .||||..:|.||:.::::|:..|:.:..|||||.|||.:|.||:|.|:.|....|.....|:::.
 Frog   229 FLLLPSPNRNLLKLLLDLLYQTARKQDRNKMSAHNLALMFAPHIIWPKNLTASDLQEHLIKLNNG 293

  Fly   290 VTYMIVRGLDIFEVPGKLSTDIRAYFLERKRKKTMSPEQTLD----ESISDVSTVNTVYTFV--- 347
            ||:||.....:|:.|..:....|.||   ...:|.:.:..||    :|.||       |.|.
 Frog   294 VTFMIKHSQKLFKAPPYIREYARLYF---SGSRTPASKDDLDLLPAQSSSD-------YHFQKHP 348

  Fly   348 --DRAATAAATNTN-------NTDTELAQLYAHIQSMPESSKKRRLIKQFNKQNGQGTPLQLVVM 403
              .|..::.:::|:       :|:..|.:|:.|:.:||:|:||:|||:|||| |...||:....:
 Frog   349 KRSRIGSSPSSSTSVQEQTQQHTEEALKELFRHVHNMPDSAKKKRLIRQFNK-NTPHTPVSDAQV 412

  Fly   404 NRLKNNEATRSAKSLGDSIKKHIFHKSLMSRTPKR--VPPSFHLASGSE--TPNMSHVKPPKMRV 464
            ...|.:..:|:...:   ||:.:....:.|....|  .|.|   :.|||  ..|:.:|......|
 Frog   413 TNGKKHVRSRTFSGM---IKRKVLGGQITSEKKSRNTTPQS---SDGSEYAKENLKYVSLDSPAV 471

  Fly   465 LFQSPTPPTPTSSTITSVSLSTNTRHQLQKSISSASLKIESSSSDSSS 512
            .|             |...|..:...|::|..||.|.|....|:..:|
 Frog   472 YF-------------TRAKLKLSEDLQIRKEASSKSKKSHHMSTQETS 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP54D	NP_001261060.1	RhoGAP	107..313	CDD:295372	75/207 (36%)
arhgap19	XP_002939704.1	RhoGAP_ARHGAP19	110..317	CDD:239857	81/234 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	113	1.000	Domainoid score	I6084
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H13159
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D376367at33208
OrthoFinder	1	1.000	-	-		FOG0008267
OrthoInspector	1	1.000	-	-		oto104863
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6235
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.010