DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6484 and MAL11

DIOPT Version :9

Sequence 1:	NP_611234.1	Gene:	CG6484 / 36994	FlyBaseID:	FBgn0034247	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_011805.3	Gene:	MAL11 / 853207	SGDID:	S000003521	Length:	616	Species:	Saccharomyces cerevisiae

Alignment Length:	523	Identity:	118/523 - (22%)
Similarity:	202/523 - (38%)	Gaps:	158/523 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 WSSPVENMIT--------VNTEYGFPISSSQFGW--------VSSLLTLGATVICIPIG------ 71
            ||..|...:.        ::..|..|:...:||.        ::|...:|.. :|:..|
Yeast   109 WSILVSTTLVMEGYDTALLSALYALPVFQRKFGTLNGEGSYEITSQWQIGLN-MCVLCGEMIGLQ 172

  Fly    72 ---FAIDWIGRRPTM---LALIPPYMVGWVLMLFAKNVTMLYFGRFILGMCGGAFCVTAPMYCTE 130
               :.::::|.|.||   |.|:..|:   .::.:.|::.|:..|:.:..:..|.|...|..|.:|
Yeast   173 ITTYMVEFMGNRYTMITALGLLTAYI---FILYYCKSLAMIAVGQILSAIPWGCFQSLAVTYASE 234

  Fly   131 ITATALRGTIGSF------FQLLIVSGVL-----------YGYLVGAFLPLLTINILCAILPVIF 178
            :...|||..:.|:      |..:..||::           .||.    ||.    .|..|.|...
Yeast   235 VCPLALRYYMTSYSNICWLFGQIFASGIMKNSQENLGNSDLGYK----LPF----ALQWIWPAPL 291

  Fly   179 AIIHFFMPESPVYLAMKGRNDDAAKALQWL---RG--KDADIDDELKEILEESQKQIDMPQVNIL 238
            .|..||.||||.:|..|.|..:|.|:|..:   :|  ||..:|..||:|      ::.:.:..:|
Yeast   292 MIGIFFAPESPWWLVRKDRVAEARKSLSRILSGKGAEKDIQVDLTLKQI------ELTIEKERLL 350

  Fly   239 SSLRRPI--VLKGLG-----IAVLLQVFQQWTGINAVLF-YSASIFEDTGSDISGSDATLIIGVT 295
            :|.....  ..||:.     :|.|..|.|..:|  |||. ||...||..|   ..:|......:.
Yeast   351 ASKSGSFFNCFKGVNGRRTRLACLTWVAQNSSG--AVLLGYSTYFFERAG---MATDKAFTFSLI 410

  Fly   296 Q----VTSTLVAVAIIDKAGRRILLLISGVLMAVSTALMGVYFQLKENDPASMDNFGWLPISSIC 356
            |    :..||.:..|..:.||..:|            ..|:.||:                  :|
Yeast   411 QYCLGLAGTLCSWVISGRVGRWTIL------------TYGLAFQM------------------VC 445

  Fly   357 IFII------------------------FFSIGFGPVPWLVMAELFSEDVKSVAGSIAGTSNWLS 397
            :|||                        |::.|.|.|.:.::||:.|.::::....:|.....|.
Yeast   446 LFIIGGMGFGSGSSASNGAGGLLLALSFFYNAGIGAVVYCIVAEIPSAELRTKTIVLARICYNLM 510

  Fly   398 AFVVTLLFPIL----------KSSIGPGPTFW-IFTAIAVIAFFYSLFFVPETKGKTIIEIQDLL 451
            |.:..:|.|.:          |:.:     :| .|||:.:.   :.:..:|||.|:|..||.:|.
Yeast   511 AVINAILTPYMLNVSDWNWGAKTGL-----YWGGFTAVTLA---WVIIDLPETTGRTFSEINELF 567

  Fly   452 SGG 454
            :.|
Yeast   568 NQG 570

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6484	NP_611234.1	Sugar_tr	14..451	CDD:278511	116/518 (22%)
CG6484	NP_611234.1	MFS	14..436	CDD:119392	109/503 (22%)
MAL11	NP_011805.3	SP	81..563	CDD:273317	114/514 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342275
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740