Protein Alignment CG6484 and VPS73

DIOPT Version :10

• Sequence 1: NP_611234.1
• Gene: CG6484 / 36994
• FlyBaseID: FBgn0034247
• Length: 465
• Species: Drosophila melanogaster
• Sequence 2: NP_011411.3
• Gene: VPS73 / 852774
• SGDID: S000003072
• Length: 486
• Species: Saccharomyces cerevisiae
• Alignment Length: 420
• Identity: 109/420 - (25%)
• Similarity: 187/420 - (44%)
• Gaps: 46/420 - (10%)

  Fly    46 PISSSQFGWVSSLLTLGATVICIPIGFAIDWIGRRPTMLALIPPYMVGWVLMLFAKNVTMLYFGR 110
            |::..|.|.|:|:..:|..:.........:..||:.:.|......:||.:::..:.:...|..||
Yeast    85 PLNDEQIGIVTSVFCIGGILGSYFATSLANIYGRKFSSLINCTLNIVGSLIIFNSNSYRGLIIGR 149

  Fly   111 FILGMCGGAFCVTAPMYCTEITATALRGTIGSFFQLLIVSGVLYGYLVGAFLPLLTINILCAIL- 174
            .::|:..|:..|..|::..|:..:...|.:||..|:.|..|||  ...|..|||........||
Yeast   150 ILVGISCGSLIVIIPLFIKEVAPSGWEGLLGSMTQICIRLGVL--LTQGIALPLTDSYRWRWILF 212

  Fly   175 -PVIFAIIHFFM----PESPVYLAMKGRNDDAAKALQWLRGKDADIDDELKEI------LEESQK 228
             ..:.|:::|||    .|||.:|...||..||..:|..|||  ...|:..:||      :|....
Yeast   213 GSFLIAVLNFFMWFIVDESPKWLLAHGRVTDAKLSLCKLRG--VTFDEAAQEIQDWQLQIESGDP 275

  Fly   229 QIDMPQVNILSS-------LRRPIVLKGLGIAVLLQVFQQWTGINAVLFYSASIFEDTGSDISGS 286
            .|:....|.:|.       ||....:|...:..:|...||:.|||:::.|...|.    |.:...
Yeast   276 LIEPTTTNSISGSNSLWKYLRDRTNVKSRHVITVLLFGQQFCGINSIVLYGTKII----SQLYPQ 336

  Fly   287 DATLI---IGVTQVTSTLVAVAIIDKAGRRILLLISGVLMAVSTALMGVYFQLKENDPASMDNFG 348
            .|..|   |.:..|..|::...:|....|:.||:.|.||::|:..:||:.....:.:...:.:|
Yeast   337 HAIRINFFISMVNVLVTILVSLLIHSLPRKPLLMTSTVLVSVTAFIMGIAMNHNKMNLLIVFSF- 400

  Fly   349 WLPISSICIFIIFFSIGFGPVPWLVMAELFSEDVKSVAGSIAGTSNWLSAFVVTLLFPILKSSIG 413
                    |::..|::|..|:|:::|.|:.......:|.......||:..|::...|||:...:
Yeast   401 --------IYMGVFTMGLNPLPFIIMREVSKPQDMVLAQRYGTICNWVGTFIIAYTFPIIHDVL- 456

  Fly   414 PGPTFWIFTAIAVIAFFYSLFF---VPETK 440
               :.::|...|:||...|.|.   |||||
Yeast   457 ---SGYVFIIFAIIACSISAFIWKKVPETK 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6484	NP_611234.1	MFS_GLUT6_8_Class3_like	10..446	CDD:340916	109/420 (26%)
VPS73	NP_011411.3	MFS_GLUT_Class1_2_like	31..484	CDD:340915	109/420 (26%)