DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6484 and MAL31

DIOPT Version :9

Sequence 1:	NP_611234.1	Gene:	CG6484 / 36994	FlyBaseID:	FBgn0034247	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_009857.1	Gene:	MAL31 / 852601	SGDID:	S000000502	Length:	614	Species:	Saccharomyces cerevisiae

Alignment Length:	481	Identity:	113/481 - (23%)
Similarity:	203/481 - (42%)	Gaps:	91/481 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 YGFPISSSQFGWVSS----------------LLTLGATVICIPI-GFAIDWIGRRPTM-LALIPP 89
            |..|:...::|.::|                |..:...::.:.: |.::|::|.|.|: :||.
Yeast   124 YALPVFQKKYGSLNSNTGDYEISVSWQIGLCLCYMAGEIVGLQMTGPSVDYMGNRYTLIMALF-- 186

  Fly    90 YMVGWVLML-FAKNVTMLYFGRFILGMCGGAF-CVTAPMYCTEITATALRGTIGSFFQLLIVSGV 152
            ::..::.:| |.|::.|:..|:.:.||..|.| |:|. .|.:||...|||..:.::..|....|.
Yeast   187 FLAAFIFILYFCKSLGMIAVGQALCGMPWGCFQCLTV-SYASEICPLALRYYLTTYSNLCWAFGQ 250

  Fly   153 LY--GYL-----------VGAFLPLLTINILCAILPVIFAIIHFFMPESPVYLAMKGRNDDAAKA 204
            |:  |.:           :|..||.    .|..|.|:..|:..||.||||.:|..|||.|.|.::
Yeast   251 LFAAGIMKNSQNKYANSELGYKLPF----ALQWIWPLPLAVGIFFAPESPWWLVKKGRIDQARRS 311

  Fly   205 LQ-WLRGKDADID-------DELKEILEESQKQIDMPQVNILSSLRRPIVLKGLGIAVLLQVFQQ 261
            |: .|.||..:.:       |::|..:|:.||..|  :......::..|..:...||.|..:.|.
Yeast   312 LERTLSGKGPEKELLVSMELDKIKTTIEKEQKMSD--EGTYWDCVKDGINRRRTRIACLCWIGQC 374

  Fly   262 WTGINAVLFYSASIFEDTGSDISGSDATLIIGVTQ----VTSTLVAVAIIDKAGRRILLLISGVL 322
            ..|. :::.||...:|..|   ..:|......:.|    :.:|.::.......||..|.......
Yeast   375 SCGA-SLIGYSTYFYEKAG---VSTDTAFTFSIIQYCLGIAATFISWWASKYCGRFDLYAFGLAF 435

  Fly   323 MAVSTALMGVYFQLKENDPASMDNFGWLPISSICIFII--FFSIGFGPVPWLVMAELFSEDVKSV 385
            .|:...::|        .....|..|....|...:.::  |:::|..||.:.:::|:.|..:::.
Yeast   436 QAIMFFIIG--------GLGCSDTHGAKMGSGALLMVVAFFYNLGIAPVVFCLVSEIPSSRLRTK 492

  Fly   386 AGSIAGTSNWLSAFVVTLLFPI----------LKSSIGPGPTFWIFTAIAVIAFFYSLFFVPETK 440
            ...:|..:..:...|||:|...          .||..     ||....:|.:|  :::..:|||.
Yeast   493 TIILARNAYNVIQVVVTVLIMYQLNSEKWNWGAKSGF-----FWGGFCLATLA--WAVVDLPETA 550

  Fly   441 GKTIIEIQDLLSGG------KGVKSD 460
            |:|.|||.:|...|      |..|.|
Yeast   551 GRTFIEINELFRLGVPARKFKSTKVD 576

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6484	NP_611234.1	Sugar_tr	14..451	CDD:278511	108/464 (23%)
CG6484	NP_611234.1	MFS	14..436	CDD:119392	100/449 (22%)
MAL31	NP_009857.1	SP	74..557	CDD:273317	106/460 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342276
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830