DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6484 and VVS1

DIOPT Version :9

Sequence 1:	NP_611234.1	Gene:	CG6484 / 36994	FlyBaseID:	FBgn0034247	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_009800.1	Gene:	VVS1 / 852543	SGDID:	S000000445	Length:	488	Species:	Saccharomyces cerevisiae

Alignment Length:	497	Identity:	144/497 - (28%)
Similarity:	213/497 - (42%)	Gaps:	108/497 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 GSVLPQY---IAGLSASFGALCMGASIGWSSPVENMITVNTEYG-------FPISSSQFGWVSSL 58
            ||:  ||   ||.|:|....|....   :.:|.||:...:|..|       ..::.||:|.::|:
Yeast    34 GSI--QYGYHIAELNAPQEFLSCSR---FEAPDENISYDDTWVGQHGLKQCIALTDSQYGAITSI 93

  Fly    59 LTLGATVICIPIG--FAIDW---IGRRPTMLALIPPYMVGWVLMLFAKNVTMLYFGRFILGM-CG 117
            .::|..     .|  :|.:|   .||:...:......||..:|:.|:.:...|.||||::|| ||
Yeast    94 FSIGGL-----FGSYYAGNWANRYGRKYVSMGASAMCMVSSLLLFFSNSYLQLLFGRFLVGMSCG 153

  Fly   118 GAFCVTAPMYCTEITATALRGTIGSFFQLLIVSGVL--------------YGYLVGAFLPLLTIN 168
            .|..:| |::..||.....||.:||..|:.|..|:|              :.:|:.:...:...|
Yeast   154 TAIVIT-PLFINEIAPVEWRGAMGSMNQVSINLGILLTQTLALKYADSYNWRWLLFSGSVIAVAN 217

  Fly   169 ILCAILPVIFAIIHFFMPESPVYLAMKGRNDDAAKAL----------------QWLRGKDADIDD 217
            || |.|.|         .|||.:|...|...:|..||                .|.|....:.|.
Yeast   218 IL-AWLKV---------DESPRWLVSHGFVSEAETALFKLRPGTYQQAKQEIQDWQRSHGHNRDP 272

  Fly   218 ELKE-----------ILEESQKQIDMPQVNILSSLRRPIVLKGLGIAVLLQVFQQWTGINAVLFY 271
            |..|           :.:.|.|:   |:..||:.|.                .||:.|||:::||
Yeast   273 ESSEETHSGPTLWQYVTDPSYKK---PRTVILAILS----------------CQQFCGINSIIFY 318

  Fly   272 SASIFEDTGSDISGSDATLIIGVTQVTSTLVAVAIIDKAGRRILLLISGVLMAVSTALMGVYFQL 336
            ...:......|.| ......|.:..|..||.|.||||..|||.|||.|..:|...:.|:.|...|
Yeast   319 GVKVIGKILPDYS-IQVNFAISILNVVVTLAASAIIDHVGRRPLLLASTTVMTAMSLLISVGLTL 382

  Fly   337 KENDPASMDNFGWLPISSICIFIIFFSIGFGPVPWLVMAELFSEDVKSVAGSIAGTSNWLSAFVV 401
                     :..:|.:::..::|..|:||.||:|:|::.||......:.|.|.....|||:.|:|
Yeast   383 ---------SVSFLLVTATFVYIAAFAIGLGPIPFLIIGELSYPQDAATAQSFGTVCNWLATFIV 438

  Fly   402 TLLFPILKSSIGPGPTFWIFTAIAVIAFFYSLFFVPETKGKT 443
            ..||||....:| |..|.||.|||.:...|....||||||||
Yeast   439 GYLFPIGHGLMG-GYVFAIFAAIAAMFATYVYKRVPETKGKT 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6484	NP_611234.1	Sugar_tr	14..451	CDD:278511	138/484 (29%)
CG6484	NP_611234.1	MFS	14..436	CDD:119392	130/475 (27%)
VVS1	NP_009800.1	MFS_GLUT_Class1_2_like	28..478	CDD:340915	141/494 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342267
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	3	2.840