DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6484 and STL1

DIOPT Version :9

Sequence 1:	NP_611234.1	Gene:	CG6484 / 36994	FlyBaseID:	FBgn0034247	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_010825.3	Gene:	STL1 / 852149	SGDID:	S000002944	Length:	569	Species:	Saccharomyces cerevisiae

Alignment Length:	488	Identity:	125/488 - (25%)
Similarity:	205/488 - (42%)	Gaps:	111/488 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 ITVNTEYGFPISSSQFGWVSSLLT------------------------LGATVICIPIG------ 71
            ||:.:..||.:.....|.::||:|                        .|||..|..:|
Yeast    31 ITIASMTGFSLFGYDQGLMASLITGKQFNYEFPATKENGDHDRHATVVQGATTSCYELGCFAGSL 95

  Fly    72 ---FAIDWIGRRPTMLALIPPYMVGWVLMLFAKNVTMLYF-----------GRFILGMCGGAFCV 122
               |..:.|||:|.:|       :|.|:.:....::...|           ||.:.|:..|....
Yeast    96 FVMFCGERIGRKPLIL-------MGSVITIIGAVISTCAFRGYWALGQFIIGRVVTGVGTGLNTS 153

  Fly   123 TAPMYCTEITATALRGTIGSFFQLLIVSGVLYGYLVGAFLPL----------LTINILCAILPVI 177
            |.|::.:|::....||.:.:.....|..|.:..|.:...|..          :::.|:.|:..:.
Yeast   154 TIPVWQSEMSKAENRGLLVNLEGSTIAFGTMIAYWIDFGLSYTNSSVQWRFPVSMQIVFALFLLA 218

  Fly   178 FAIIHFFMPESPVYLAMKGRNDDAAKALQWLRG--KDADIDDELKEILEE--------SQKQIDM 232
            |.|   .:||||.:|..:.|.::|    ::|.|  .|||.:||  |::.|        ::.:.:.
Yeast   219 FMI---KLPESPRWLISQSRTEEA----RYLVGTLDDADPNDE--EVITEVAMLHDAVNRTKHEK 274

  Fly   233 PQVNILSSLRRPIVLKGLGIAVLLQVFQQWTGINAVLFYSASIFEDT-------GSDISGSDATL 290
            ..::.|.|..|...|:...||...|.|||:||.||.::||..:|..|       ...|.|..||:
Yeast   275 HSLSSLFSRGRSQNLQRALIAASTQFFQQFTGCNAAIYYSTVLFNKTIKLDYRLSMIIGGVFATI 339

  Fly   291 IIGVTQVTSTLVAVAIIDKAGRRILLLISGVLMAVSTALMGVYFQLKENDPASMDNFGWLPISSI 355
                 ...||:.:..:|:|.|||.|.|:.....|||..:..... :|||    .:|.....: .:
Yeast   340 -----YALSTIGSFFLIEKLGRRKLFLLGATGQAVSFTITFACL-VKEN----KENARGAAV-GL 393

  Fly   356 CIFIIFFSIGFGPVPWLVMAELFSEDVKSVAGSIAGTSNWLSAFVVTLLFPILKSSIGPGPTFWI 420
            .:||.||.:....:||:...|:.|..|::...:.:..:|||..|.|.:..||.....|.|  .::
Yeast   394 FLFITFFGLSLLSLPWIYPPEIASMKVRASTNAFSTCTNWLCNFAVVMFTPIFIGQSGWG--CYL 456

  Fly   421 FTA------IAVIAFFYSLFFVPETKGKTIIEI 447
            |.|      |.||.|||     |||.|:::.||
Yeast   457 FFAVMNYLYIPVIFFFY-----PETAGRSLEEI 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6484	NP_611234.1	Sugar_tr	14..451	CDD:278511	125/488 (26%)
CG6484	NP_611234.1	MFS	14..436	CDD:119392	119/475 (25%)
STL1	NP_010825.3	Sugar_tr	32..488	CDD:395036	124/487 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm13432
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	4	3.810