DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6484 and SNF3

DIOPT Version :9

Sequence 1:	NP_611234.1	Gene:	CG6484 / 36994	FlyBaseID:	FBgn0034247	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_010087.1	Gene:	SNF3 / 851333	SGDID:	S000002353	Length:	884	Species:	Saccharomyces cerevisiae

Alignment Length:	506	Identity:	145/506 - (28%)
Similarity:	233/506 - (46%)	Gaps:	80/506 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KGSVLPQYIAGLSASFGALCMGASIGWSSPVENMITVNTEYGFP----ISSSQFGWVSSLLTLGA 63
            |.|::.....|:..:.|....|...|..:.:.:|..|.:... |    .::.|...:.|.|:||.
Yeast    91 KQSMMMSICVGVFVAVGGFLFGYDTGLINSITSMNYVKSHVA-PNHDSFTAQQMSILVSFLSLGT 154

  Fly    64 TVICIPIGFAIDWIGRRPTML-ALIPPYMVGWVLMLFAKNVTMLYFGRFILGMCGGAFCVTAPMY 127
            ....:...|..|..||:||:: :.|..:.:|..|.:.|..:|:|..||.|.|:..||.....|:|
Yeast   155 FFGALTAPFISDSYGRKPTIIFSTIFIFSIGNSLQVGAGGITLLIVGRVISGIGIGAISAVVPLY 219

  Fly   128 CTEITATALRGTIGSFFQ------LLIVSGVLYG-----------------YLVGAFLPLLTINI 169
            ..|.|..:|||.|.|.:|      ||:.|.|..|                 |:..:||
Yeast   220 QAEATHKSLRGAIISTYQWAITWGLLVSSAVSQGTHARNDASSYRIPIGLQYVWSSFL------- 277

  Fly   170 LCAILPVIFAIIHFFMPESPVYLAMKGRNDDAAKALQWLRG---KDADIDDELKEILEESQKQID 231
                     ||..||:||||.|..:|.:.|:|||:|.:|||   .|:.:.:||.||......:..
Yeast   278 ---------AIGMFFLPESPRYYVLKDKLDEAAKSLSFLRGVPVHDSGLLEELVEIKATYDYEAS 333

  Fly   232 MPQVN----ILSSLRRPIVLKGLGIAVLLQVFQQWTGINAVLFYSASIFEDTGSDISGSDATLII 292
            ....|    .:||..||.....:...:.||.|||::|||.:.:|..:.|..||.    |::.|:.
Yeast   334 FGSSNFIDCFISSKSRPKQTLRMFTGIALQAFQQFSGINFIFYYGVNFFNKTGV----SNSYLVS 394

  Fly   293 GVTQVTSTLVAVA---IIDKAGRRILLLISGVLMAVSTALMGVY-FQLKENDPASMDNFGWLPIS 353
            .:|...:.:..|.   .::..|||.:|::.||:|.::..::.:. ..||....|.      :.|:
Yeast   395 FITYAVNVVFNVPGLFFVEFFGRRKVLVVGGVIMTIANFIVAIVGCSLKTVAAAK------VMIA 453

  Fly   354 SICIFIIFFSIGFGPVPWLVMAELFSEDVKSVAGSIAGTSNWLSAFVVTLLFPIL------KSSI 412
            .||:||..||..:|.|.|::.|||:...|:|...:|...:|||..|:..|:.|.:      .||:
Yeast   454 FICLFIAAFSATWGGVVWVISAELYPLGVRSKCTAICAAANWLVNFICALITPYIVDTGSHTSSL 518

  Fly   413 GPGPTFWIF---TAIAVIAFFYSLFFVPETKGKTIIEIQDL-LSGGKGVKS 459
            | ...|:|:   .|:.||..:.:::   ||||.|:.||.:| :....||.|
Yeast   519 G-AKIFFIWGSLNAMGVIVVYLTVY---ETKGLTLEEIDELYIKSSTGVVS 565

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6484	NP_611234.1	Sugar_tr	14..451	CDD:278511	139/485 (29%)
CG6484	NP_611234.1	MFS	14..436	CDD:119392	131/469 (28%)
SNF3	NP_010087.1	MFS_HXT	99..556	CDD:340914	139/487 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342261
Domainoid	1	1.000	165	1.000	Domainoid score	I819
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm13432
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	6	5.740