DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6484 and YFL040W

DIOPT Version :9

Sequence 1:	NP_611234.1	Gene:	CG6484 / 36994	FlyBaseID:	FBgn0034247	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_116613.1	Gene:	YFL040W / 850503	SGDID:	S000001854	Length:	540	Species:	Saccharomyces cerevisiae

Alignment Length:	498	Identity:	113/498 - (22%)
Similarity:	198/498 - (39%)	Gaps:	111/498 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 TVNTEYGFP--------ISSSQFGWVSSLLTLGATVICIPIGFAIDWIGRRPTMLALIPPYMVGW 94
            |.|..:.:|        :.|:..|.:     :|..:.||        :..|.:.:......::.|
Yeast    54 TFNEYFKYPTPLQQGLLMGSTPLGGI-----MGCFICCI--------MNDRFSRIYQFQSGIIIW 105

  Fly    95 VLMLFAKNVTMLYF----------GRFILGMCGGAFCVTAPMYCTEITATALRGTIGSFFQLLIV 149
            .:      ||:|.|          .|.|.||..|.|.:....|..|:.....||:..|:.||.:.
Yeast   106 NI------VTLLNFCIWDILGLLICRMIKGMILGNFSILVASYANEVIPRGKRGSTMSYIQLCLT 164

  Fly   150 SGVLYGYLVGAFLPL------LTINILCAILP-VIFAIIHFFMPESPVYLAMKGRNDDAAKALQW 207
            .|:|..:.:...|.|      ..|.....|:| ::|.:..:.:|||..:|.:.|:..:|
Yeast   165 IGILVMHYLCIALSLWDSHFAFRIAWCIGIIPGLLFWMASYALPESYHWLVLHGKMSEA------ 223

  Fly   208 LRGKDADIDDELKEILEESQKQIDMPQ-------------VNILSSLR-------RPIVLKGLGI 252
                 .:|...|.:...|||.:..:|:             ||.|...:       :|::|
Yeast   224 -----QEIQHNLAKKFNESQPRDAVPEMSKIELAGDFWIGVNDLDFSKKLPRGSFKPLIL----- 278

  Fly   253 AVLLQVFQQWTGINAVLFYSASIFEDTG--SDISGSDATLIIGVTQVTSTLVAVAIIDKAGRRIL 315
            .:.||:..|::|||.:|.|...|.|..|  .::....:::...:..|.| |:.:..||...|:::
Yeast   279 GMTLQLLVQFSGINIILGYITYICEIVGLEGNVKLFTSSIPYFINMVLS-LLPITFIDYTSRKLI 342

  Fly   316 LLISGVLMAVSTALMGVYFQLKENDPASMDN--------------FGWLPISSICIFII-FFSIG 365
            .|:.|..::.....:|..|.....|...:|.              .||  |.::|..|: .|::.
Yeast   343 TLLGGFPISGLLITIGALFVKYGQDTKPIDGNRSLVWSIGENPFVGGW--ILTLCFLIVGIFAMS 405

  Fly   366 FGPVPWLVMAELFSEDVKSVAGSIAGTSNWLSAFVVTLLFPILKSSIGPGPTFWIFTAIAVIAFF 430
            ...:||:...|:....||....:|..|..||..|::|.|.|::...: .|.||.||.::..:...
Yeast   406 LSSIPWVYTNEMLPSRVKVKGFAICVTFGWLGNFILTFLCPVMIERL-KGTTFIIFGSLTFLISL 469

  Fly   431 YSLFFVPETKGKTIIEIQDL----------LSGGKGVKSDDKS 463
            ..|.:.|||||.:|.:|...          |.|.||:|:.|.:
Yeast   470 SVLIWFPETKGMSIEDIDKFFEFESKEGTNLHGEKGIKTPDSN 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6484	NP_611234.1	Sugar_tr	14..451	CDD:278511	107/484 (22%)
CG6484	NP_611234.1	MFS	14..436	CDD:119392	100/459 (22%)
YFL040W	NP_116613.1	MFS_HXT	28..490	CDD:340914	107/474 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900