DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6484 and INT4

DIOPT Version :9

Sequence 1:	NP_611234.1	Gene:	CG6484 / 36994	FlyBaseID:	FBgn0034247	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_001328028.1	Gene:	INT4 / 827346	AraportID:	AT4G16480	Length:	582	Species:	Arabidopsis thaliana

Alignment Length:	547	Identity:	134/547 - (24%)
Similarity:	229/547 - (41%)	Gaps:	121/547 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LSASFGALCMGASIGWSSPVENMITVNTEYGFPISSSQFGWVSSLLTLGATVICIPIGFAI---- 74
            |||..|.|..|...|..|.....|           ...|..|.....|.:|::.:.:..||
plant    32 LSAGIGGLLFGYDTGVISGALLFI-----------KEDFDEVDKKTWLQSTIVSMAVAGAIVGAA 85

  Fly    75 --DWI----GRRPTMLALIPPYMVGWVLMLFAKNVTMLYFGRFILGMCGGAFCVTAPMYCTEITA 133
              .||    |||.::|.....:::|.::|.||....::..||..:|...|...:|:|:|.:|.:.
plant    86 VGGWINDKFGRRMSILIADVLFLIGAIVMAFAPAPWVIIVGRIFVGFGVGMASMTSPLYISEASP 150

  Fly   134 TALRGTIGSFFQLLIVSGVLYGYLV--------GAFLPLLTINILCAILPVIFAIIHFFMPESPV 190
            ..:||.:.|...|||..|..:.||:        |.:..:|.:   ..:..::..::...:||||.
plant   151 ARIRGALVSTNGLLITGGQFFSYLINLAFVHTPGTWRWMLGV---AGVPAIVQFVLMLSLPESPR 212

  Fly   191 YLAMKGRNDDAAKALQWLRGKDADIDDELKEI-----LEESQKQI--DMPQVNILSSLRRPIVLK 248
            :|..|.|..::...|:.:...| :::.|::.:     .|::.:.|  |.....:..:...|:|.:
plant   213 WLYRKDRIAESRAILERIYPAD-EVEAEMEALKLSVEAEKADEAIIGDSFSAKLKGAFGNPVVRR 276

  Fly   249 GLGIAVLLQVFQQWTGINAVLFYSASIFEDTG--SDISGSDATLIIGVTQVTSTLVAVAIIDKAG 311
            ||...:.:||.||:.|||.|::||.||.:..|  |:.:....:||........::|::..:|:.|
plant   277 GLAAGITVQVAQQFVGINTVMYYSPSIVQFAGYASNKTAMALSLITSGLNALGSIVSMMFVDRYG 341

  Fly   312 RRILLLIS--GV---LMAVST-----------------------ALMGVYFQL-KENDPASMDN- 346
            ||.|::||  |:   |:.::|                       |....|..| .||.|.|..|
plant   342 RRKLMIISMFGIIACLIILATVFSQAAIHAPKIDAFESRTFAPNATCSAYAPLAAENAPPSRWNC 406

  Fly   347 -------------------------------------------------FGWLPISSICIFIIFF 362
                                                             ||:|.|..:.::|:.:
plant   407 MKCLRSECGFCASGVQPYAPGACVVLSDDMKATCSSRGRTFFKDGCPSKFGFLAIVFLGLYIVVY 471

  Fly   363 SIGFGPVPWLVMAELFSEDVKSVAGSIAGTSNWLSAFVVTLLFPILKSSIGPGPTFWIFTAIAVI 427
            :.|.|.|||:|.:|::....:.:.|.||..|||:|..:|:..|..|..::|...||.:|...:.|
plant   472 APGMGTVPWIVNSEIYPLRYRGLGGGIAAVSNWVSNLIVSESFLSLTHALGSSGTFLLFAGFSTI 536

  Fly   428 AFFYSLFFVPETKGKTIIEIQDLLSGG 454
            ..|:....||||||....|::.||..|
plant   537 GLFFIWLLVPETKGLQFEEVEKLLEVG 563

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6484	NP_611234.1	Sugar_tr	14..451	CDD:278511	131/542 (24%)
CG6484	NP_611234.1	MFS	14..436	CDD:119392	124/527 (24%)
INT4	NP_001328028.1	MFS_HMIT_like	33..547	CDD:340918	124/528 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810