Protein Alignment CG6484 and SLC2A10

DIOPT Version :10

• Sequence 1: NP_611234.1
• Gene: CG6484 / 36994
• FlyBaseID: FBgn0034247
• Length: 465
• Species: Drosophila melanogaster
• Sequence 2: XP_011527362.1
• Gene: SLC2A10 / 81031
• HGNCID: 13444
• Length: 562
• Species: Homo sapiens
• Alignment Length: 542
• Identity: 131/542 - (24%)
• Similarity: 219/542 - (40%)
• Gaps: 140/542 - (25%)

  Fly     6 VLPQYIAGLSASFGALCMGASIGWSSPVEN--MITVNTEYGFPISSSQFGWVSSLLTLGATVICI 68
            |||     |.||. :|..|.:.|:...|.:  ::.:..::|......:| .|.||| |||.:..:
Human    28 VLP-----LCASV-SLLGGLTFGYELAVISGALLPLQLDFGLSCLEQEF-LVGSLL-LGALLASL 84

  Fly    69 PIGFAIDWIGRRPTMLALIPPYMVGWVLMLFAKNVTMLYFGRFILGMCGGAFCVTAPMYCTEITA 133
            ..||.||..||:..:|......:.|.:.:..|.::..|..||.::|.......:...:|.:|:..
Human    85 VGGFLIDCYGRKQAILGSNLVLLAGSLTLGLAGSLAWLVLGRAVVGFAISLSSMACCIYVSELVG 149

  Fly   134 TALRGTIGSFFQLLIVSGVLYGYLVGAFLPLLTINILCAILP--------------VIFAIIHFF 184
            ...||.:.|.::..|..|:|..|         .:|...|..|              |:.::...|
Human   150 PRQRGVLVSLYEAGITVGILLSY---------ALNYALAGTPWGWRHMFGWATAPAVLQSLSLLF 205

  Fly   185 MPESPVYLAMKGRNDDAA-KALQWLRGKDADIDDELKEILEESQKQIDMPQVNILSSLRRPIVLK 248
            :|        .|.::.|. |.|..|:|.:|            .:.....|:.:.|...|....::
Human   206 LP--------AGTDETATHKDLIPLQGGEA------------PKLGPGRPRYSFLDLFRARDNMR 250

  Fly   249 G---LGIAVLLQVFQQWTGINAVLFYSASIFEDTGSDISGSDATLI---IGVTQVTSTLVAVAII 307
            |   :|:.::|  |||.||...||.|:::||...|.. .||.|.|.   :|..:|.:||.|:.::
Human   251 GRTTVGLGLVL--FQQLTGQPNVLCYASTIFSSVGFH-GGSSAVLASVGLGAVKVAATLTAMGLV 312

  Fly   308 DKAGRRILLLISGVLMAVSTALMG-VYFQL----------------------------------- 336
            |:||||.|||....|||:|.:.:| |.|.:
Human   313 DRAGRRALLLAGCALMALSVSGIGLVSFAVPMDSGPSCLAVPNATGQTGLPGDSGLLQDSSLPPI 377

  Fly   337 ----------------------KENDPASMDNFG-------------------WLPISSICIFII 360
                                  :..||::.....                   |..:..:.:|:.
Human   378 PRTNEDQREPILSTAKKTKPHPRSGDPSAPPRLALSSALPGPPLPARGHALLRWTALLCLMVFVS 442

  Fly   361 FFSIGFGPVPWLVMAELFSEDVKSVAGSIAGTSNWLSAFVVTLLFPILKSSIGPGPTFWIFTAIA 425
            .||.|||||.|||::|::..:::..|.:...:.||.:...::|.|..|..:||...||.::...|
Human   443 AFSFGFGPVTWLVLSEIYPVEIRGRAFAFCNSFNWAANLFISLSFLDLIGTIGLSWTFLLYGLTA 507

  Fly   426 VIAFFYSLFFVPETKGKTIIEI 447
            |:...:...|||||||:::.||
Human   508 VLGLGFIYLFVPETKGQSLAEI 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6484	NP_611234.1	MFS_GLUT6_8_Class3_like	10..446	CDD:340916	126/535 (24%)
SLC2A10	XP_011527362.1	MFS_GLUT10_Class3	31..529	CDD:340994	126/532 (24%)