DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6484 and slc2a10

DIOPT Version :9

Sequence 1:	NP_611234.1	Gene:	CG6484 / 36994	FlyBaseID:	FBgn0034247	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_001072926.1	Gene:	slc2a10 / 780388	XenbaseID:	XB-GENE-950490	Length:	555	Species:	Xenopus tropicalis

Alignment Length:	539	Identity:	142/539 - (26%)
Similarity:	227/539 - (42%)	Gaps:	123/539 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 IAGLSASFGALCMGASIGWSSPVENMITVNTEYGFPISSSQFGWVSSLLTLGATVICIPIGFAID 75
            :|...:..|.:..|..:|..|..  ::.:.|.|.. ....|...||::| .||.:..:..|..||
Frog    10 LAATVSLLGGIVFGYELGIISGA--LLVLKTVYQL-TCFEQEALVSAVL-FGALLASLIGGIIID 70

  Fly    76 WIGRRPTMLALIPPYMVGWVLMLFAKNVTMLYFGRFILGMCGGAFCVTAPMYCTEITATALRGTI 140
            ..|||..:||.....:.|.::::.......|..||..:|.......:...:|.:||.....||.:
Frog    71 RWGRRTAILASNLVVLAGSIILIATSTFWWLIVGRVTIGFAISISSMACCIYVSEIVRPHQRGML 135

  Fly   141 GSFFQLLIVSGVLYGYLVGAFLPLLTIN------ILCAILPVIFAIIH-FFMPESPVYLAMKGRN 198
            .|.::..|..|:|..|.:..||.  .:|      ...||:|..|..|. .|:|..|..|..
Frog   136 VSLYETGITVGILISYAMNYFLS--GVNESWKYMFGLAIVPAAFQFISILFLPSKPHKLNF---- 194

  Fly   199 DDAAKALQWLRGKDADIDD---ELKEILEESQKQIDM--PQVNILSSLR-----RPIVLKGLGIA 253
                    |    :.|.||   ||:|..|..:.:.|.  .|...|...|     |...|.|||
Frog   195 --------W----EQDTDDGFIELEETGEAGEFKPDTYDRQYTFLDLFRSKDNMRTRTLLGLG-- 245

  Fly   254 VLLQVFQQWTGINAVLFYSASIFEDTG--SDISGSDATLIIGVTQVTSTLVAVAIIDKAGRRILL 316
              |.:|||:||...||:|:::||:..|  |:.|...|::.:||.:|.|||:|:...|||||||||
Frog   246 --LVLFQQFTGQPNVLYYASTIFQSVGFQSNSSAVLASVGLGVVKVASTLIAICFADKAGRRILL 308

  Fly   317 LISGVLMAVSTALMG-VYFQLKEND---------------------------------------- 340
            |...::|.::...:| |.|.:|.:.
Frog   309 LAGCIVMTIAITGIGIVSFTVKMDSHRDCGSVTGRNMSSGESNVSQLLGIVHAETSTINTLDNSV 373

  Fly   341 -------------------------------PASMD---NF---GWLPISSICIFIIFFSIGFGP 368
                                           |||.:   |:   .|:.:.|:..|:..|||||||
Frog   374 HQLAMAIRSPSLANSASSNHKDLISQNSTVLPASPELPSNYTILNWITLLSMMAFVSAFSIGFGP 438

  Fly   369 VPWLVMAELFSEDVKSVAGSIAGTSNWLSAFVVTLLFPILKSSIGPGPTFWIFTAIAVIAFFYSL 433
            :.|:|::|::..|::..|.:...:.||.:..::||.|..:.:|||...||.::..:.::|..:..
Frog   439 MTWIVLSEIYPADIRGRAFAFCNSFNWAANLLITLTFLDVIASIGLSWTFLLYGVVGLLAIAFIY 503

  Fly   434 FFVPETKGKTIIEIQDLLS 452
            ||:|||||:::.||....|
Frog   504 FFIPETKGQSLEEIDKQFS 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6484	NP_611234.1	Sugar_tr	14..451	CDD:278511	140/533 (26%)
CG6484	NP_611234.1	MFS	14..436	CDD:119392	132/518 (25%)
slc2a10	NP_001072926.1	MFS_GLUT10_Class3	10..517	CDD:340994	139/532 (26%)
		Monosaccharide binding. /evidence=ECO:0000250\|UniProtKB:P11166	250..256		4/5 (80%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	528..555
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D524131at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920