Protein Alignment CG6484 and SLC2A1

DIOPT Version :9

• Sequence 1: NP_611234.1
• Gene: CG6484 / 36994
• FlyBaseID: FBgn0034247
• Length: 465
• Species: Drosophila melanogaster
• Sequence 2: NP_006507.2
• Gene: SLC2A1 / 6513
• HGNCID: 11005
• Length: 492
• Species: Homo sapiens
• Alignment Length: 479
• Identity: 166/479 - (34%)
• Similarity: 245/479 - (51%)
• Gaps: 50/479 - (10%)

  Fly    16 ASFGALCMGASIGWSSPVENMI------TVNTEYGFPISSSQFGWVSSL----LTLGATVICIPI 70
            |..|:|..|.:.|..:..:.:|      |....||..|..:....:.||    .::|..:....:
Human    19 AVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTTLTTLWSLSVAIFSVGGMIGSFSV 83

  Fly    71 GFAIDWIGRRPTMLALIPPYMVGWVLMLFA---KNVTMLYFGRFILGMCGGAFCVTAPMYCTEIT 132
            |..::..|||.:||.:.....|..|||.|:   |:..||..||||:|:..|......|||..|::
Human    84 GLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFIIGVYCGLTTGFVPMYVGEVS 148

  Fly   133 ATALRGTIGSFFQLLIVSGVLYGYLVG-----------------AFLPLLTINILCAILPVIFAI 180
            .|||||.:|:..||.||.|:|...:.|                 .|:|.|   :.|.:||
Human   149 PTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKDLWPLLLSIIFIPAL---LQCIVLP----- 205

  Fly   181 IHFFMPESPVYLAMKGRNDDAAKA-LQWLRGKDADIDDELKEILEESQKQIDMPQVNILSSLRRP 244
               |.||||.:|.:....::.||: |:.||| .||:..:|:|:.|||::.:...:|.||...|.|
Human   206 ---FCPESPRFLLINRNEENRAKSVLKKLRG-TADVTHDLQEMKEESRQMMREKKVTILELFRSP 266

  Fly   245 IVLKGLGIAVLLQVFQQWTGINAVLFYSASIFEDTGSDISGSDATLIIGVTQVTSTLVAVAIIDK 309
            ...:.:.|||:||:.||.:|||||.:||.||||..|.. ....||:..|:.....|:|::.::::
Human   267 AYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQ-QPVYATIGSGIVNTAFTVVSLFVVER 330

  Fly   310 AGRRILLLISGVLMAVSTALMGVYFQLKENDPASMDNFGWLPISSICIFIIFFSIGFGPVPWLVM 374
            ||||.|.||....||....||.:...|.|..|.    ..:|.|.:|..|:.||.:|.||:||.::
Human   331 AGRRTLHLIGLAGMAGCAILMTIALALLEQLPW----MSYLSIVAIFGFVAFFEVGPGPIPWFIV 391

  Fly   375 AELFSEDVKSVAGSIAGTSNWLSAFVVTLLFPILKSSIGPGPTFWIFTAIAVIAFFYSLFFVPET 439
            |||||:..:..|.::||.|||.|.|:|.:.|..::...|| ..|.|||.:.|:.|.::.|.||||
Human   392 AELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQYVEQLCGP-YVFIIFTVLLVLFFIFTYFKVPET 455

  Fly   440 KGKTIIEIQDLLSGGKGVKSDDKS 463
            ||:|..||......| |....||:
Human   456 KGRTFDEIASGFRQG-GASQSDKT 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6484	NP_611234.1	Sugar_tr	14..451	CDD:278511	162/465 (35%)
		MFS	14..436	CDD:119392	153/450 (34%)
SLC2A1	NP_006507.2	MFS_GLUT_Class1	14..458	CDD:340989	158/456 (35%)
		Monosaccharide binding. /evidence=ECO:0000269|PubMed:24847886	282..288		3/5 (60%)
		Disordered. /evidence=ECO:0000305|PubMed:30197081	468..492		4/12 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143914
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.840