DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6484 and slc2a11b

DIOPT Version :9

Sequence 1:	NP_611234.1	Gene:	CG6484 / 36994	FlyBaseID:	FBgn0034247	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	XP_005165088.1	Gene:	slc2a11b / 564970	ZFINID:	ZDB-GENE-070705-96	Length:	522	Species:	Danio rerio

Alignment Length:	503	Identity:	143/503 - (28%)
Similarity:	228/503 - (45%)	Gaps:	82/503 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SKGSVLPQYIAGLSASFGALCMGASIGW----SSPVENMI--TVNTEYGFPISSSQFG--W--VS 56
            ||..:|..:.||:..:|.   .|.:|..    :..|:|.|  |....|...|||....  |  :.
Zfish    40 SKYLLLAVWAAGIGGTFQ---YGYNISIINAPTKAVQNFINQTWTERYSTEISSDMLTLLWSIIV 101

  Fly    57 SLLTLGATVICIPIGFAIDWIGRRPTML-----ALIPPYMVGWVLMLFAKNVTMLYFGRFILGMC 116
            |:.|:|..|.....|......||:.|:|     ||:....:|  |...|....:|..|||:.|:.
Zfish   102 SIFTIGGLVGASVGGTLAIRFGRKGTLLFNNTFALLAALFMG--LSYPASTFELLVIGRFLTGVN 164

  Fly   117 GG-AFCVTAPMYCTEITATALRGTIGSFFQLLIVSGVLYGYLVG--------AFLPLLTINILCA 172
            .| |.|| .|:|..||...||||.:.....:.|..|:|.|.::|        .:.|:| ::.:|
Zfish   165 AGIAICV-QPLYIGEIAPRALRGAMAMGTSIFITGGILTGQVMGLKELLGKDEYWPIL-LSTIC- 226

  Fly   173 ILPVIFAIIHF-FMPESPVYLAMKGRNDDAA--KALQWLRGKD---ADIDDELKEILEESQKQID 231
             :|.:..::.. :.||||.||.: .|.||.|  |||.|..|:|   .:::|            |:
Zfish   227 -IPAVLQLLTLPWFPESPRYLLI-DRGDDIACQKALMWFHGQDKYHGEMED------------IE 277

  Fly   232 MPQVNILS-------------SLRRPIVLKGLGIAVLLQVFQQWTGINAVLFYSASIFEDTG-SD 282
            ..:|:.|.             |:|..::     ..|::...||..||||:.||:..:|...| .|
Zfish   278 RERVSALGIKPKKPWELFTDRSIRWQLL-----TLVVIHTSQQLNGINAIYFYADYVFTQAGIPD 337

  Fly   283 ISGSDATLIIGVTQVTSTLVAVAIIDKAGRRILLLISGVLMAVSTALMGVYFQLKENDPASMDNF 347
            .....||:..|..:..:.|....:|:..|||.|::....||:|......:....:::.|
Zfish   338 DKIPYATVGTGACECITALTCGLLIESLGRRALIIGGYTLMSVCCICFTIALTFQDSSP------ 396

  Fly   348 GWLP-ISSICI--FIIFFSIGFGPVPWLVMAELFSEDVKSVAGSIAGTSNWLSAFVVTLLFPILK 409
             |:| :|.:|:  ||:.|.:|.|.|..::..|||::..:..|..|.|:.||.|.||:.::||.:.
Zfish   397 -WVPYLSMVCVLAFILSFGLGPGGVTNILTTELFTQTDRPAAYMIGGSINWTSFFVIGMIFPFIV 460

  Fly   410 SSIGPGPTFWIFTAIAVIAFFYSLFFVPETKGKTIIEIQDLLSGGKGV 457
            :.: ....|.:|..|.::...|..|.|||||.||.:|||:.....|.:
Zfish   461 NGL-KQYCFLVFLVICLLVATYIFFVVPETKNKTFLEIQNEFKSRKKI 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6484	NP_611234.1	Sugar_tr	14..451	CDD:278511	137/483 (28%)
CG6484	NP_611234.1	MFS	14..436	CDD:119392	127/468 (27%)
slc2a11b	XP_005165088.1	Sugar_tr	54..501	CDD:278511	137/481 (28%)
slc2a11b	XP_005165088.1	MFS	98..486	CDD:119392	115/419 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576864
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840