DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6484 and slc2a11l

DIOPT Version :9

Sequence 1:	NP_611234.1	Gene:	CG6484 / 36994	FlyBaseID:	FBgn0034247	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_001073485.1	Gene:	slc2a11l / 564849	ZFINID:	ZDB-GENE-061215-118	Length:	504	Species:	Danio rerio

Alignment Length:	513	Identity:	142/513 - (27%)
Similarity:	220/513 - (42%)	Gaps:	113/513 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSKGSVLPQ--YIAGLSASFGALCMGASIG-WSSP---VENMI--TVNTEYGFPIS----SSQFG 53
            ::|..||..  .|||:..:|.   .|.:|. .:||   ::.::  |....||..:.    |..:.
Zfish     8 LTKSPVLVAAILIAGIGGTFQ---YGFNISVLNSPSPFIKELVNSTCQQRYGHSLEPWELSLIWS 69

  Fly    54 WVSSLLTLGATVICIPIGFAIDWIGRRPTMLALIPPYMVGWVLMLFAK---NVTMLYFGRFILGM 115
            ::.|:.::|.....:..|......||:.|:|......:.|.:||||:|   :..|:...|.:.|:
Zfish    70 FIVSIYSIGGLAGTLYAGRVAGMYGRKTTLLLNNVLAISGAILMLFSKTALSFEMIMVARVLYGI 134

  Fly   116 CGGAFCVTAPMYCTEITATALRGTIG----SFF-------QLLIVSGVL---YGYL-------VG 159
            ..|.......||..|.....|||.:|    ||.       |||.:|.||   .|::       ..
Zfish   135 NAGVSLTVHTMYILECAPKRLRGMVGVSVASFVSLGKFSGQLLGISEVLGTEQGWIWLLAFSGAA 199

  Fly   160 AFLPLLTINILCAILPVIFAIIHFFMPESPVYLAM-KGRNDDAAKALQWLRGKDADIDDELKEIL 223
            ..|.|||       ||        |:||||.||.: |........||:.|.|.:.|...|::|:|
Zfish   200 GLLQLLT-------LP--------FLPESPRYLLLEKADKHGCETALRRLWGTERDPGPEMEEML 249

  Fly   224 EESQKQIDMPQVNILSSLRRPIVLKGLGIAVLLQVF------------------QQWTGINAVLF 270
            .|.                  ..|||:.|..|:.:|                  .|..|||||..
Zfish   250 AEH------------------AALKGVKIHRLMDLFLDHNVRWQLFTIIVTFITLQLCGINAVYL 296

  Fly   271 YSASIFEDTGSDISGSD---ATLIIGVTQVTSTLVAVAIIDKAGRRILLLISGVLMAVSTALMGV 332
            ||..:|:..|  |:..:   |.|..|:.:|::::..|.||:..|:|:||....:.||.|.||:.:
Zfish   297 YSFDVFQAAG--IAKENLRYAALGTGLCEVSTSIACVLIIESTGKRLLLFRGYICMAASLALLTL 359

  Fly   333 YFQLKENDPASMDNFGWLPISS---ICIFIIFFSIGFGPVPWLVMAELFSEDVKSVAGSIAGTSN 394
            ...|:       |...|:|..|   :.|:|.|||.|...|...:..|:|::..|..|..:|...|
Zfish   360 TLYLQ-------DFVSWMPYCSMVLVFIYIFFFSSGPAGVTAPLPGEIFTQSYKPPAFVVACVLN 417

  Fly   395 WLSAFVVTLLFPILKSSIGPGPTFWIFTAIAVIAFF---YSLFFVPETKGKTIIEIQD 449
            |:..|:|.:|||::...:    .::.|....|..||   :..|.|||||.||::||.:
Zfish   418 WIGLFLVGMLFPLIVEHL----DYFCFLVFFVFCFFSGVFVWFHVPETKNKTVLEITE 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6484	NP_611234.1	Sugar_tr	14..451	CDD:278511	136/498 (27%)
CG6484	NP_611234.1	MFS	14..436	CDD:119392	127/483 (26%)
slc2a11l	NP_001073485.1	Sugar_tr	19..473	CDD:278511	139/502 (28%)
slc2a11l	NP_001073485.1	MFS	69..>200	CDD:119392	33/130 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576870
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840