DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6484 and slc2a6

DIOPT Version :9

Sequence 1:	NP_611234.1	Gene:	CG6484 / 36994	FlyBaseID:	FBgn0034247	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	XP_689092.6	Gene:	slc2a6 / 560602	ZFINID:	ZDB-GENE-081104-301	Length:	490	Species:	Danio rerio

Alignment Length:	473	Identity:	138/473 - (29%)
Similarity:	231/473 - (48%)	Gaps:	29/473 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 YIAGLSASFGALCMGASIGWSSPVENMITVNTEYGFPISSSQFGWVSSLLTLGATVICIPIGFAI 74
            |:|..||..|....|.::.:.|||...:....:....::..|..|..|:.||||....:...|..
Zfish    25 YLAVFSAVLGNFNFGFALVFPSPVIPQLKQGDDTRLQMNVHQISWFGSIFTLGAAAGGLSAMFLN 89

  Fly    75 DWIGRRPTMLALIPPYMVGWVLMLFAKNVTMLYFGRFILGMCGGAFCVTAPMYCTEITATALRGT 139
            |.:||:.:::....|.::|.::|..|:|..||.:|||:.|:.||....:.|:|.:||:..::||.
Zfish    90 DRVGRKISIMISGLPSVLGLLVMGSAQNFWMLLWGRFLTGIAGGITAGSIPVYVSEISHPSVRGA 154

  Fly   140 IGSFFQLLIVSGVLYGYLVGAFLPLLTINILCAILPVIFAIIHFFMPESPVYLAMKGRNDDAAKA 204
            :||..|:..|.|.|..|..|..||...:.:...:..||..::...||.||.|..|||....|.|:
Zfish   155 LGSCPQITAVFGSLALYAFGLILPWRWLAVAGEVPVVIMMLLLCCMPTSPRYHIMKGNRAKAVKS 219

  Fly   205 LQWLRGKDADIDDELKEILEESQKQIDMPQVNILSSLRRPIVLKGLGIAVLLQVFQQWTGINAVL 269
            |:||||.::|...|..:|    ::.|....|. .|.|:.....|.:.|:|:::..||.|||..:|
Zfish   220 LEWLRGPNSDYMTEFNKI----ERSITTQGVQ-WSDLKTKSYYKPILISVVMRFLQQMTGITPIL 279

  Fly   270 FYSASIFEDTGSDISGSDATLIIGVTQVTSTLVAVAIIDKAGRRILLLISGVLMAVSTALMGVYF 334
            .|...||..|...:.......::|..::.|..:|.:::|||||:.||..||.|:.::...|.:|
Zfish   280 VYLEPIFHLTAISLEPKYDAALVGAVRLISVAIAASLMDKAGRKALLFTSGFLIYIAMLSMTMY- 343

  Fly   335 QLKENDPASMDNF---------------------GWLPISSICIFIIFFSIGFGPVPWLVMAELF 378
              ....|.|..|.                     ..:|:.|..:.|..:::|:||:.||:|:|:.
Zfish   344 --THQTPCSQGNLTLTDGLNISSEVQAGAAFDPKTLIPLISAMVIIFGYAMGWGPITWLLMSEIL 406

  Fly   379 SEDVKSVAGSIAGTSNWLSAFVVTLLFPILKSSIGPGPTFWIFTAIAVIAFFYSLFFVPETKGKT 443
            ....:.||..:....:|::|||:|.||..:..:.|....|..|..::|:...::...||||||:|
Zfish   407 PLGARGVASGLCVGVSWITAFVLTQLFMHVVVAYGLYVPFLFFCVVSVVNIIFTAKCVPETKGRT 471

  Fly   444 IIEIQDLLSGGKGVKSDD 461
            :.||::....|:.....|
Zfish   472 LEEIENYFRTGRSFTIHD 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6484	NP_611234.1	Sugar_tr	14..451	CDD:278511	134/457 (29%)
CG6484	NP_611234.1	MFS	14..436	CDD:119392	125/442 (28%)
slc2a6	XP_689092.6	Sugar_tr	27..479	CDD:278511	135/459 (29%)
slc2a6	XP_689092.6	MFS	28..461	CDD:119392	125/440 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576882
Domainoid	1	1.000	292	1.000	Domainoid score	I1492
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	311	1.000	Inparanoid score	I2576
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	1	1.000	-	-		FOG0000275
OrthoInspector	1	1.000	-	-		mtm6527
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48021
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.900