DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6484 and Glut3

DIOPT Version :9

Sequence 1:	NP_611234.1	Gene:	CG6484 / 36994	FlyBaseID:	FBgn0034247	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_536732.1	Gene:	Glut3 / 42036	FlyBaseID:	FBgn0015230	Length:	507	Species:	Drosophila melanogaster

Alignment Length:	466	Identity:	142/466 - (30%)
Similarity:	225/466 - (48%)	Gaps:	51/466 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 YIAGLSASFGALCMGASIGWSSPVENMITVNTEYGFPISSSQFGWVSSLLTLGATVICIPIGFAI 74
            |.|.|.::.|:...|.::|||...|..:.....|.|..:..|:..|..||||||.:.|:|:|..:
  Fly    52 YKATLYSNIGSFFFGIAVGWSGTAERSVMEQHSYSFQPTELQWSGVCILLTLGAALWCLPMGLMV 116

  Fly    75 DWIGRRPTMLALIPPYMVGWVLMLFAKNVTMLYFGRFILGMCGGAFCVTAPMYCTEITATALRGT 139
            ..:|.|.|:|..:.|..:||.|.:||::|.|||.|||.|||||||.||..|:|..||:.|..||.
  Fly   117 RLLGCRRTILIQLLPNFLGWFLTVFARSVPMLYAGRFFLGMCGGAHCVVVPIYNAEISTTKKRGA 181

  Fly   140 IGSFFQLLIVSGVLYGYLVGAFLPLLTINI----LCAILPVIFAIIHFFMPESPVYLAMKGRNDD 200
            :|..|:...:.||:|.:.:..||.|..||.    |.|:.|     :...|||||.|....|....
  Fly   182 MGVVFEGACICGVIYSFAMSLFLELRIINFVNLGLLALGP-----LQILMPESPAYYVDHGNIPR 241

  Fly   201 AAKALQWLRGKDADIDDELKEILE---ESQKQIDM-PQVNILSSLRRPIVLKGLGIAVLLQVFQQ 261
            |..:|::|||:..|...|:..:..   ||::::.. |.:.......|..:.:.|.||:|    |:
  Fly   242 AEDSLRFLRGQKYDTRREIDFLTRDPTESEREVRQGPLLGFKYKKVRRSLARSLAIALL----QK 302

  Fly   262 WTGINAVLFYSASIFE------DTGSDISGSDATLIIGVTQVTSTLVAVAIIDKAGRRILLLISG 320
            ..|....:||..::.:      :.|         ||:.:..:...|....::|:.|||.||:.|.
  Fly   303 LCGALIFIFYGLNMLDCLRIRREFG---------LILCLGLILGFLACFFLVDRLGRRPLLIFSS 358

  Fly   321 VLMAVSTALMGVYFQLKENDPASMDNFGWLPISSICIFIIFFSIGFGPVPWLVMAELFSEDVKSV 385
            ..:...:..:|::|::...  ..:....|:.:..|.||:..::.|.|.:.|::.|||....::.:
  Fly   359 AGIVFVSIYLGLHFKVWMT--MGLTVMSWIALFCIAIFVGCYTAGVGSLTWVLNAELLVRPMRPL 421

  Fly   386 AGSIAGTSNWLSAFVVTLLF--------PILKSSIGPGPTFWIFTAIAVIAFFYSLFFVPETKGK 442
            ..||....|||:||.|...|        |.|         |.:|..||.:...:||.::||||..
  Fly   422 GCSIVCAFNWLTAFFVICWFGSHGVKCQPYL---------FLLFAIIASLILLFSLIYIPETKKL 477

  Fly   443 TIIEIQDLLSG 453
            :..:||..|.|
  Fly   478 SSAKIQQRLGG 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6484	NP_611234.1	Sugar_tr	14..451	CDD:278511	138/458 (30%)
CG6484	NP_611234.1	MFS	14..436	CDD:119392	132/443 (30%)
Glut3	NP_536732.1	Sugar_tr	60..484	CDD:278511	136/452 (30%)
Glut3	NP_536732.1	MFS	63..>226	CDD:119392	64/167 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444281
Domainoid	1	1.000	165	1.000	Domainoid score	I819
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	1	1.000	-	-		FOG0000275
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48021
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
	8	7.850