DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6484 and CG31100

DIOPT Version :9

Sequence 1:	NP_611234.1	Gene:	CG6484 / 36994	FlyBaseID:	FBgn0034247	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_001262395.1	Gene:	CG31100 / 41075	FlyBaseID:	FBgn0051100	Length:	716	Species:	Drosophila melanogaster

Alignment Length:	606	Identity:	123/606 - (20%)
Similarity:	234/606 - (38%)	Gaps:	167/606 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LPQYIA-----------GLSASFGALCMGASIGWSSPVENMITVNTEYGFPISSSQFGWVSSLLT 60
            |||::|           |::..|..:.:.|..|.....|      |.....::..:..|.||:
  Fly    48 LPQFLAVSIKNILLFGYGMTLGFPTIVIPAIQGGEGRSE------TSGDILLNKDEISWFSSI-- 104

  Fly    61 LGATVICIPIGFAIDW-----IGRRPTMLALIPPYMVGWVLMLFAKNVTMLYFGRFILGMCGGAF 120
               .:||:|:|.....     :|:|..|..:..|.:..|::..||.....||....:.|:.||..
  Fly   105 ---NLICVPLGCLFSGLLTQPLGKRRAMQFVNLPILAAWLMFHFATRTEHLYAALCLAGLGGGLM 166

  Fly   121 CVTAPMYCTEITATALRGTIGSFFQLLIVSGVLYGYLVGAFLPLLTINILCAILPVIFAIIHFFM 185
            ......|..|||....||.:.:.....:::||...:::|:.:...::..:.:..|||..|:..|:
  Fly   167 EAPVLTYVAEITEPKYRGILSALGTTCVITGVFIQFILGSLMDWRSVAAVSSAFPVITIIMLCFV 231

  Fly   186 PESPVYLAMKGRNDDAAKALQWLRG--KDADIDDELKEILEE--SQKQIDMP--------QVNIL 238
            |||||:|..:.|..:|.|:||||||  .:..|:.|..::.:|  :||.|::.        |...|
  Fly   232 PESPVWLIREQRFREAVKSLQWLRGWVPEHMIEAEFNQLYDELITQKAIELSADGIPPPGQRRTL 296

  Fly   239 SSLRRPIVLKGLGIAVLLQVFQQWT----GINAVLFYSASIFEDTGSDISGSDATLIIGVTQVTS 299
            ....|....:...:..||..|..:|    |...:..|:..||....:.::...||:::||.::.:
  Fly   297 GQRLRMWRKRSFLVPFLLVSFSFFTGHFSGKTPLQTYAVQIFHTLKAPMNKYHATILLGVAEMLA 361

  Fly   300 TLVAVAIIDKAGRRILLLISGV--------------------------LMAVSTALM---GV--- 332
            |::.|.:|...|:|.|:|:|.|                          ::..::::|   |:
  Fly   362 TILGVVLIHFTGKRPLVLVSTVGTGLCFFGTATYAHFLSEVPGFTVNNVVVNASSIMPKEGILSQ 426

  Fly   333 -----YFQLKEN--------------------------------------------------DPA 342
                 .|:.::.                                                  :|:
  Fly   427 QNISKIFETEQQAIRQETERFTTQLPDIETTTLFDQEIYNRSRRDVVEMMTTDAPMDTTMWPEPS 491

  Fly   343 SM---------------------------------DNFGWLPISSICIFIIFFSIGFGPVPWLVM 374
            |.                                 :...|:|:..:.:...|..:|...:||:::
  Fly   492 SSPEPIASSSLAPPSTSVKPPLVEELLLVVPKQEHNYLVWVPLILLLLSAFFSHLGIRMLPWILI 556

  Fly   375 AELFSEDVKSVAGSIAGTSNWLSAFVVTLLFPILKSSIGPGPTFWIFTAIAVIAFFYSLFFVPET 439
            .|:|..::::.|...||...::..|:...||.::.|::....||..:.::|........|.:|||
  Fly   557 GEVFPAEIRNSASGFAGGVGYIFGFLANKLFLLMLSALTLPGTFAFYASVAFFGTVVLYFTLPET 621

  Fly   440 KGKTIIEIQDLLSGGKGVKSD 460
            :|:|:.||:...|    .|||
  Fly   622 EGRTLGEIEAHFS----KKSD 638

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6484	NP_611234.1	Sugar_tr	14..451	CDD:278511	114/577 (20%)
CG6484	NP_611234.1	MFS	14..436	CDD:119392	107/562 (19%)
CG31100	NP_001262395.1	MFS	59..>232	CDD:119392	39/183 (21%)
		Sugar_tr	98..633	CDD:278511	109/539 (20%)
		MFS	<531..616	CDD:119392	18/84 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48021
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920