DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6484 and Slc2a10

DIOPT Version :9

Sequence 1:	NP_611234.1	Gene:	CG6484 / 36994	FlyBaseID:	FBgn0034247	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_001102433.1	Gene:	Slc2a10 / 366251	RGDID:	1306552	Length:	536	Species:	Rattus norvegicus

Alignment Length:	548	Identity:	136/548 - (24%)
Similarity:	220/548 - (40%)	Gaps:	152/548 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 SVLPQYIAGLSASFGALCMGASIGWSSPVENMITVNTEYGFPISSSQFGWVSSLLTLGATVICIP 69
            :|||     |.||. :|..|.:.|:...|.:...:..:..|.:|..:...:...|.|||.:..:.
  Rat     6 TVLP-----LCASV-SLLGGLTFGYELAVISGALLPLQLDFRLSCLEQELLVGSLLLGAFLASLV 64

  Fly    70 IGFAIDWIGRRPTMLALIPPYMVGWVLMLFAKNVTMLYFGR----FILGMCGGAFCVTAPMYCTE 130
            .||.||..|||..:|......:.|.:::..|.::..|..||    |.:.:...|.|:    |.:|
  Rat    65 GGFLIDCYGRRRAILGSNVVLLAGSLILGLAGSLPWLLLGRSSVGFAISLSSMACCI----YVSE 125

  Fly   131 ITATALRGTIGSFFQLLIVSGVLYGYLVGAFLPLLTINILCAILP--------------VIFAII 181
            :.....||.:.|.:::.|..|:|:.|         .:|.:.|..|              ::.::.
  Rat   126 LVGPRQRGVLVSLYEVGITVGILFSY---------GLNYVLAGSPWGWRHMFGWAAAPALLQSLS 181

  Fly   182 HFFMPESPVYLAMKGRNDDAAKA-LQWLRGKDADIDDELKEILEESQKQIDMPQVNILSSLR--- 242
            .||:|        .|....||:. |..|:|.            |.|:..:...|...|...|
  Rat   182 LFFLP--------AGAEGTAARQDLIPLQGG------------ETSKLGLVKAQYTFLDLFRAQD 226

  Fly   243 ----RPIVLKGLGIAVLLQVFQQWTGINAVLFYSASIFEDTGSDISGSDATLI---IGVTQVTST 300
                |.:|  |||    |.:|||.||...||:|:::||...|.. .||.|.|.   :|..:|.:|
  Rat   227 GMWSRTVV--GLG----LVLFQQLTGQPNVLYYASTIFRSVGFH-GGSSAVLASVGLGTVKVVAT 284

  Fly   301 LVAVAIIDKAGRRILLLISGVLMAVS--------------------------------------- 326
            |:|..::|:.|||.|||....|||:|
  Rat   285 LIATGLVDRVGRRALLLSGCALMALSVSGIGLVSFAVSLDSGPSCLATSNTSQQVDLPQTPGLLV 349

  Fly   327 ------------------------------TALMGVYFQLKENDPAS----MDNFGWLPISSICI 357
                                          ||.:|....:..:.|.|    .....|..:..:.:
  Rat   350 RTSLPPVLHTSGDQGQPVRSVTERPIHPVITASLGPALNIDSSVPTSPIPEHTLLCWSALVCMMV 414

  Fly   358 FIIFFSIGFGPVPWLVMAELFSEDVKSVAGSIAGTSNWLSAFVVTLLFPILKSSIGPGPTFWIF- 421
            ::..||.|||||.|||::|::..:::..|.:...:.||.:...::|.|..|..:||...||.::
  Rat   415 YVSAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCSSFNWAANLFISLSFLDLIGAIGLAWTFLLYG 479

  Fly   422 -TAIAVIAFFYSLFFVPETKGKTIIEIQ 448
             ||:..:||.|.|  ||||||:::.||:
  Rat   480 LTAVLGLAFIYLL--VPETKGQSLAEIE 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6484	NP_611234.1	Sugar_tr	14..451	CDD:278511	133/539 (25%)
CG6484	NP_611234.1	MFS	14..436	CDD:119392	125/525 (24%)
Slc2a10	NP_001102433.1	Sugar_tr	11..508	CDD:278511	132/538 (25%)
Slc2a10	NP_001102433.1	MFS	14..>330	CDD:119392	89/356 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337692
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D524131at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.750