DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6484 and Slc2a12

DIOPT Version :9

Sequence 1:	NP_611234.1	Gene:	CG6484 / 36994	FlyBaseID:	FBgn0034247	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_849265.2	Gene:	Slc2a12 / 353169	MGIID:	3052471	Length:	622	Species:	Mus musculus

Alignment Length:	556	Identity:	135/556 - (24%)
Similarity:	243/556 - (43%)	Gaps:	127/556 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 YIAGLSASFGALCMGASIGWSSPVENMITVNTEYGFPISSSQFGWVSSLLTLGATVICIPIGFAI 74
            ::..::|:...|.:|..:|..|..  ::.:.|.........:. .||||| :||.:..:..|..|
Mouse    45 FLTSVTAAISGLLVGYELGLISGA--LLQIRTLLALTCHEQEM-VVSSLL-IGAFLASLTGGVLI 105

  Fly    75 DWIGRRPTMLALIPPYMVGWVLMLFAKNVTMLYFGRFILGMCGGAFCVTAPMYCTEITATALRGT 139
            |..|||..::.......:|.::::.:.:.|:|..||..:|:......:...:|..||.....||.
Mouse   106 DRYGRRLAIILSSCLLGLGSLVLIMSLSYTLLIMGRVAIGVSISLSSIATCVYIAEIAPQHRRGL 170

  Fly   140 IGSFFQLLIVSGVLYG---------------YLVGAFLPLLTINILCAILPVIFAIIHFFMPESP 189
            :.|..:|:||:|:|:.               |:.|..:|          |.|:.||..:|:|.||
Mouse   171 LVSLNELMIVTGILFAYISNYAFANISNGWKYMFGLVIP----------LGVLQAIAMYFLPPSP 225

  Fly   190 VYLAMKGRNDDAAKALQWLRGKDADIDDELKEILEESQKQIDMPQVNILSSLR-----RPIVLKG 249
            .:|.|||:.:.|.|.|:.|| ..:|..:|| .:::.|.|  |..|.:.....|     |..:|.|
Mouse   226 RFLVMKGQEESAGKVLRKLR-VISDTTEEL-TLIKSSLK--DEYQYSFWDLFRSKDNMRTRILIG 286

  Fly   250 LGIAVLLQVFQQWTGINAVLFYSASIFEDTG--SDISGSDATLIIGVTQVTSTLVAVAIIDKAGR 312
            |    .|..|.|.||...:|||::::.:..|  |:.:.|.|:..:||.:|.||:.|..::|..|.
Mouse   287 L----TLVFFVQTTGQPNILFYASTVLKSVGFQSNEAASLASTGVGVVKVVSTIPATLLVDHIGS 347

  Fly   313 RILLLISGVLMAVSTALMG---------------------------VYF----------QLKEN- 339
            :..|.|...:|:.|...||                           |::          .|:|:
Mouse   348 KTFLCIGSSVMSASLLTMGIVNLNINMNFTNICRSHSLLNQSLEEFVFYATGNLSISNSSLREHF 412

  Fly   340 ------------------DP-------ASMDNFG--------------------WLPISSICIFI 359
                              :|       :|:.|.|                    ||.::|:.:::
Mouse   413 KRITPYSKGSFMPMGNGMEPKGEMTFTSSLPNAGLSRTEHQGVTDTAVVPAAYKWLSLASLLVYV 477

  Fly   360 IFFSIGFGPVPWLVMAELFSEDVKSVAGSIAGTSNWLSAFVVTLLFPILKSSIGPGPTFWIFTAI 424
            ..||||.||:||||::|:|...::..|.::..:.||....:::|.|..:...||.....:|:|.:
Mouse   478 AAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGVNLLISLTFLTVTDLIGLSWVCFIYTIM 542

  Fly   425 AVIAFFYSLFFVPETKGKTIIEIQDLLSGGKGVKSD 460
            ::.:..:.:.|:|||||.::.:|...|:....||::
Mouse   543 SLASLAFVVLFIPETKGCSLEQISVELAKANYVKNN 578

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6484	NP_611234.1	Sugar_tr	14..451	CDD:278511	132/541 (24%)
CG6484	NP_611234.1	MFS	14..436	CDD:119392	125/526 (24%)
Slc2a12	NP_849265.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..26
		Sugar_tr	48..569	CDD:278511	132/542 (24%)
		MFS	49..>367	CDD:119392	93/339 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834161
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.840