DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6484 and itr1

DIOPT Version :9

Sequence 1:	NP_611234.1	Gene:	CG6484 / 36994	FlyBaseID:	FBgn0034247	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_593858.2	Gene:	itr1 / 2543145	PomBaseID:	SPAC4F8.15	Length:	575	Species:	Schizosaccharomyces pombe

Alignment Length:	509	Identity:	130/509 - (25%)
Similarity:	231/509 - (45%)	Gaps:	77/509 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 YIAGLSASFGALCMGASIGWSSPVENMITVNTEY-GFPISSSQFGWVSSLLTLGATVICIPIGFA 73
            ::...:|..|.|..|...|..|..  ::.:.|.. |..:::....:::|..:|||.:..|..|..
pombe    88 WVLAFAAGIGGLLFGYDTGVISGA--LVVIGTSLGGHELTNGGKEFITSATSLGALLGGIIAGAL 150

  Fly    74 IDWIGRRPTMLALIPPYMVGWVLMLFAKNVTMLYFGRFILGMCGGAFCVTAPMYCTEITATALRG 138
            .|:.||:|.:.......:||.::.:.|.::..:..|||::|...|...:..|:|.:||..:.:||
pombe   151 ADFFGRKPVIAIASIIIIVGSIVQVTAHHLWHMIVGRFVIGWGVGIASLIIPLYLSEIAPSKIRG 215

  Fly   139 TIGSFFQLLIVSG--VLYG-------------YLVGAFLPLLTINILCAILPVIFAI-IHFFMPE 187
            .:...:.|||.:|  :.||             ::||           .|::|..|.: |..::||
pombe   216 RLVIIYVLLITAGQVIAYGIDTAFEHVHNGWRWMVG-----------LAMVPAAFQLFILIWLPE 269

  Fly   188 SPVYLAMKGRNDDAAKAL---------QWLRGKDADIDDELKEILEESQKQIDMPQVNILSSLR- 242
            ||..|..|.|:.:|...|         ..::.|...|.:.:::....|:.|      .|:.:.:
pombe   270 SPRLLVKKERSQEAYNTLARIYPTAHPYEIKTKLYLIQEGVRDPFSGSRWQ------KIVKTFKE 328

  Fly   243 ---RPIVLKGLGIAVLLQVFQQWTGINAVLFYSASIFEDTGSDISGSDAT-LIIGVTQVTSTLVA 303
               .|...:.|.:|..||..||.:|.|:::::|::|||..|  .:...|| |||..|....|:||
pombe   329 LYFNPSNFRALILACGLQAMQQLSGFNSLMYFSSTIFEVVG--FNNPTATGLIIAATNFVFTIVA 391

  Fly   304 VAIIDKAGRRILLLIS--GVLMAVSTALMGVYFQLKE---NDPASMDNFGW--LPISSICIFIIF 361
            ..:||..|||||||::  |::.|:....:..:|..|:   |..:...| .|  :.:.|:.:::..
pombe   392 FGVIDFFGRRILLLLTVWGMIAALIVCAVAFHFLPKDENGNYTSGQSN-AWAIVVLISMIVYVAS 455

  Fly   362 FSIGFGPVPWLVMAELFSEDVKSVAGSIAGTSNWLSAFVVTLLFPILKSSIGPGPTFWIFTAIAV 426
            ::.|.|.:|| ..:|||...|:.:...::...||.....:...|..|.|.|.|..||.::..:..
pombe   456 YASGLGNLPW-QQSELFPMSVRGLGTGMSTAVNWAGNLGIGASFLTLMSEITPTGTFALYGGLCF 519

  Fly   427 IAFFYSLFFVPETKGKTIIEIQDLLSGGKGVKS----------------DDKSQ 464
            :.:..:||..|:....||.||.:||..|.||:.                :||.|
pombe   520 LGWLGALFCYPDLTDYTIEEIGELLKHGFGVRESMRHLKRVRQERAWSREDKEQ 573

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6484	NP_611234.1	Sugar_tr	14..451	CDD:278511	122/474 (26%)
CG6484	NP_611234.1	MFS	14..436	CDD:119392	117/459 (25%)
itr1	NP_593858.2	Sugar_tr	90..544	CDD:278511	122/476 (26%)
itr1	NP_593858.2	MFS	92..529	CDD:119392	117/459 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	179	1.000	Domainoid score	I819
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	184	1.000	Inparanoid score	I1095
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm13833
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.860