DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6484 and ght7

DIOPT Version :9

Sequence 1:	NP_611234.1	Gene:	CG6484 / 36994	FlyBaseID:	FBgn0034247	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_001018762.2	Gene:	ght7 / 2541736	PomBaseID:	SPBC1348.14c	Length:	518	Species:	Schizosaccharomyces pombe

Alignment Length:	454	Identity:	118/454 - (25%)
Similarity:	199/454 - (43%)	Gaps:	68/454 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 NMITVNTEYGFPISSSQFGWVSSLLTLGATVICIPIGFAIDWIGRRPTMLALIPPYMVG------ 93
            |.||.:..|    |||:.|.::.::.:|:...|:......|.||:|.:::.....|::|
pombe    13 NQITNSYSY----SSSRQGLITGMVNVGSFFGCLLSSPVADKIGKRLSIIVWTTVYLIGIIIQVT 73

  Fly    94 ----WVLMLFAKNVTMLYFGRFILGMCGGAFCVTAPMYCTEITATALRGTIGSFFQLLIVSGVLY 154
                ||.:|.||..|         |:..||..|..|.|.:|:....:||.|.:.:||.|..|:
pombe    74 TVPSWVQILVAKIWT---------GLSIGALSVITPGYQSEVAPAIMRGAIVTTYQLFITLGI-- 127

  Fly   155 GYLVGAFLPLLT----------------INILCAILPVIFAIIHFFMPESPVYLAMKGRNDDAAK 203
              .:.|.:.:.|                ||:|..|:.::..|   |:||||.||...|::|:|.|
pombe   128 --FIAACINMGTHKYSHGTTAQWRISIGINLLWGIITLVGII---FLPESPRYLIAIGKDDEALK 187

  Fly   204 ALQWLRGKDADIDDELKEILEESQKQIDMPQVNILSSLRRPIVLKG-------LGIAVLLQVFQQ 261
            .:.:  ..|..::.|:.:....:.|. |..........|.|.:...       ||:||::  |||
pombe   188 IMCY--NNDLPLEHEIIQTEYHTIKS-DCDAELAGGPARWPEIFNANIRYRTFLGMAVMM--FQQ 247

  Fly   262 WTGINAVLFYSASIFEDTGSDISGSDATLIIGVTQVTSTLVAVAIIDKAGRRILLLISGVLMAVS 326
            .||.|...:|...:|..||.| |...|.||........|..|:.:::..|||..|::.|:...:.
pombe   248 LTGANYYFYYGTQVFRGTGMD-SPYLAALIPDAVNCGCTFGAIFVLEFFGRRSPLIVGGIWQYIC 311

  Fly   327 TALMGVYFQ--LKENDPASMDNFGWLPISSICIFIIFFSIGFGPVPWLVMAELFSEDVKSVAGSI 389
            ..:......  |...:..|....|.:.|...|:||..||..:.|..::::.|.:....:|...::
pombe   312 FFIYAAVGDRALYHKNGTSNHRAGAVMIVFSCLFIFSFSQTWAPAAYVIVGESYPVRYRSKCAAV 376

  Fly   390 AGTSNWLSAFVVTLLFPILKSSIGPGPTF---WIFTAIAVIAFFYSLFFVPETKGKTIIEIQDL 450
            |.::||...|:::...|.:.:|||    |   :||.:..:........||.||||:|:.||..:
pombe   377 ATSANWFWNFLISFFTPFITNSIG----FKYGYIFASCNLTGAAIIFLFVHETKGRTLEEINTM 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6484	NP_611234.1	Sugar_tr	14..451	CDD:278511	118/454 (26%)
CG6484	NP_611234.1	MFS	14..436	CDD:119392	109/438 (25%)
ght7	NP_001018762.2	Sugar_tr	8..437	CDD:278511	118/454 (26%)
ght7	NP_001018762.2	MFS	14..422	CDD:119392	108/437 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9279
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	3	2.900