DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6484 and ght2

DIOPT Version :9

Sequence 1:	NP_611234.1	Gene:	CG6484 / 36994	FlyBaseID:	FBgn0034247	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_596425.1	Gene:	ght2 / 2539977	PomBaseID:	SPBC4B4.08	Length:	531	Species:	Schizosaccharomyces pombe

Alignment Length:	486	Identity:	112/486 - (23%)
Similarity:	205/486 - (42%)	Gaps:	85/486 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 SFGALCMGASIGWSSPVENMITVNTEYG---------FPISSSQFGWVSSLLTLGATVICIPIGF 72
            |......||..|....|.:|......|.         :.:||::.|.::.::.:|:...||....
pombe    18 SMAGWMFGADTGSIGGVTSMRDFRERYADRYDPITDQYSLSSARQGLLTGMVNVGSLFGCIISSP 82

  Fly    73 AIDWIGRRPTMLALIPPYMVG----------WVLMLFAKNVTMLYFGRFILGMCGGAFCVTAPMY 127
            ..|..|:|.:::.....|::|          ||.::.||..|         |:..||..|.||.|
pombe    83 IADRFGKRLSIIGFCAVYIIGIIVQVTAVPSWVQIMVAKIWT---------GIGIGALSVLAPGY 138

  Fly   128 CTEITATALRGTIGSFFQLLIVSGVLYGYLVGAFLPLLT--------------INILCAILPVIF 178
            .:|....::|||:...:||.:..|:    .:.|.:.:.|              ||:|..|:.:|.
pombe   139 QSETAPPSIRGTVVVTYQLFVTGGI----FIAACINMGTHKLHKTAQWRVSIGINLLWGIITMIG 199

  Fly   179 AIIHFFMPESPVYLAMKGRNDDAAKALQWLRGKDADIDDELKEILEESQKQIDMPQVNILSSLRR 243
            .:   |:||||.||...|::::|.:.|    .:.|::..:.:|:..|..:        :.||:..
pombe   200 IL---FLPESPRYLIQVGKDEEAVRVL----SESAELFPDSEEVQNEYHR--------LKSSIDE 249

  Fly   244 ----------PIVLKGLGIAVLLQVF----QQWTGINAVLFYSASIFEDTGSDISGSDATLIIGV 294
                      .|..|.:.....|.:|    ||.||.|...:|..|:.:..|.: |...:.:|:..
pombe   250 EFAGGPCSWASIFGKDIRYRTFLGMFVMSLQQLTGNNYFFYYGFSVMQGAGIN-SPYLSAMILDA 313

  Fly   295 TQVTSTLVAVAIIDKAGRRILLLISGVLMAVSTALMGVYFQ--LKENDPASMDNFGWLPISSICI 357
            .....|...:.::::.|||..|:|.|:..::...:......  |...:..|....|.:.|...|:
pombe   314 VNFGCTFGGMYVLERFGRRNPLIIGGIWQSICFFIYSAVGSRALYHKNGTSNTRAGAVMIVMACL 378

  Fly   358 FIIFFSIGFGPVPWLVMAELFSEDVKSVAGSIAGTSNWLSAFVVTLLFPILKSSIGPGPTF---W 419
            ||..|:..:.|..::::.|.:....:|...::|..||||..|:::...|.:::|||    |   :
pombe   379 FIFGFAQTWAPAAYVIVGESYPVRYRSKCAAVATASNWLWNFLISFFTPFIQASIG----FKYGY 439

  Fly   420 IFTAIAVIAFFYSLFFVPETKGKTIIEIQDL 450
            :|.:..:........|..||||.|:.||.:|
pombe   440 VFASCNLTGAIVIFLFAKETKGLTLEEINEL 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6484	NP_611234.1	Sugar_tr	14..451	CDD:278511	112/486 (23%)
CG6484	NP_611234.1	MFS	14..436	CDD:119392	103/470 (22%)
ght2	NP_596425.1	MFS	14..456	CDD:119392	103/470 (22%)
ght2	NP_596425.1	Sugar_tr	15..471	CDD:278511	112/486 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9279
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	4	3.810