DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6484 and ght5

DIOPT Version :9

Sequence 1:	NP_611234.1	Gene:	CG6484 / 36994	FlyBaseID:	FBgn0034247	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_587740.1	Gene:	ght5 / 2539240	PomBaseID:	SPCC1235.14	Length:	546	Species:	Schizosaccharomyces pombe

Alignment Length:	496	Identity:	126/496 - (25%)
Similarity:	214/496 - (43%)	Gaps:	94/496 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 SFGALCMGASIGWSSPVENMITVNTEY---------GFPISSSQFGWVSSLLTLGATVICIPIGF 72
            |......||..|....:.||....:.:         .:..||::.|.::.::.:|:...|.....
pombe    14 SMAGWMFGADTGSIGGITNMRDFQSRFADRYNPVTDSYSYSSARQGLITGMVNVGSFFGCFLSSP 78

  Fly    73 AIDWIGRRPTMLALIPPYMVG----------WVLMLFAKNVTMLYFGRFILGMCGGAFCVTAPMY 127
            .:|.||:|.:::.....|::|          ||.::.||..|         |:..||..|.||.:
pombe    79 LMDRIGKRTSIMFWTIVYLIGIILQVTAVPSWVQIMVAKIWT---------GLSIGALSVLAPGF 134

  Fly   128 CTEITATALRGTIGSFFQLLIVSGVLYGYLVGAFLPLLT--------------INILCAILPVIF 178
            .:|:....|||||.:.:||.:..|:    .:.|.:.:.|              ||:|..|:..|.
pombe   135 QSEVAPADLRGTIVTTYQLAVTGGI----FIAACINMGTHKLHKTAQWRVSMGINLLWGIITFIG 195

  Fly   179 AIIHFFMPESPVYLAMKGRNDDAAKALQWLRGKDADIDDELKEILEE-----------------S 226
            .   .|:||||.||...||:::|.:    :..|:.|:..|.:.|..|                 :
pombe   196 I---SFLPESPRYLISVGRDEEALQ----IMAKNNDLPIEHEVIQTEYHVIKSDCEAELAGGPAT 253

  Fly   227 QKQIDMPQVNILSSLRRPIVLKGLGIAVLLQVFQQWTGINAVLFYSASIFEDTGSDISGSDATLI 291
            ..:|..|.:...:.|       |||:..|    ||.||.|...:|...:||.||.: |...:.||
pombe   254 WPEIFGPDIRYRTFL-------GLGVMSL----QQLTGDNYYFYYGFEVFEGTGMN-SPYLSALI 306

  Fly   292 IGVTQVTSTLVAVAIIDKAGRRILLLISGVLMAVS---TALMGVYFQLKENDPASMDNFGWLPIS 353
            :.......|...:.:::..|||:.|:|..:..:::   .|.:|.....::|. .|....|.:.|.
pombe   307 LDAVNFGCTFGGLFVLEFFGRRMPLIIGALWQSITFFIYAAVGNRALTRKNG-TSNHRAGAVMIV 370

  Fly   354 SICIFIIFFSIGFGPVPWLVMAELFSEDVKSVAGSIAGTSNWLSAFVVTLLFPILKSSIGPGPTF 418
            ..|:||..|:..:||..::::.|.:....:|...::|.|.|||..|:::...|.:.:|||    |
pombe   371 FSCLFIFSFAQTWGPAAYVIVGESYPIRYRSKCAAVATTGNWLWGFLISFFTPFITNSIG----F 431

  Fly   419 ---WIFTAIAVIAFFYSLFFVPETKGKTIIEIQDL-LSGGK 455
               :||.|..:.|......|..||||.|:.||.:| :||.|
pombe   432 KYGYIFAACNLCAACIIFLFAHETKGLTLEEINELYISGAK 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6484	NP_611234.1	Sugar_tr	14..451	CDD:278511	123/490 (25%)
CG6484	NP_611234.1	MFS	14..436	CDD:119392	114/474 (24%)
ght5	NP_587740.1	MFS	10..451	CDD:119392	114/473 (24%)
ght5	NP_587740.1	Sugar_tr	11..467	CDD:278511	122/489 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9279
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	3	2.900