DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6484 and K08H10.6

DIOPT Version :9

Sequence 1:	NP_611234.1	Gene:	CG6484 / 36994	FlyBaseID:	FBgn0034247	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_505572.1	Gene:	K08H10.6 / 187181	WormBaseID:	WBGene00010698	Length:	479	Species:	Caenorhabditis elegans

Alignment Length:	479	Identity:	122/479 - (25%)
Similarity:	209/479 - (43%)	Gaps:	70/479 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 ASF-GALCMGASIGWSSPVENMI------TVNTEYGFPISSSQFGWV-SSL---LTLGATVICIP 69
            |:| |....|..|...:|:..::      .:...|.:.:||||...: |||   |.:||.:....
Worm    27 ATFAGGFHFGYLISAVNPLSEILQQFIVDNLQNRYSYELSSSQLSLIWSSLAGCLFIGAMIGAYI 91

  Fly    70 IGFAIDWIGRRPTMLALIPPYMVGWVLMLFAKNVTMLYFG-RFILGMC----------GGAFCV- 122
            ..|.:..||.|.::|       :..:|.||:..|    || .:.|.:|          |.||.:
Worm    92 SIFLLQSIGPRNSLL-------LAAILQLFSAPV----FGLAYSLRLCELLPISRILSGIAFAIG 145

  Fly   123 --TAPMYCTEITATALRGTIGSFFQL------LIVSGVLYGYLVGAFLP---LLTINILCAILPV 176
              ...::.|||:....||...|...|      |:.:.:...|::|....   :..|..:..:|.:
Worm   146 ISAQGVFLTEISPAKFRGLTNSLSGLIGNCAFLLAATLGTPYVLGTVTQWKYIFFIETIPCVLHI 210

  Fly   177 IFAIIHFFMPESPVYLAMKGRNDDAAKALQWLRGKDADIDDELKE--ILEESQKQIDMPQVNILS 239
            :..|..|.  :||.||...|:..:...|::...|:...|...:::  |::...|:         .
Worm   211 LVNITTFH--DSPTYLLSIGKISEGESAIKVYYGETCHIKKIMEDLRIIDNGVKE---------K 264

  Fly   240 SLRRPIVLKG----LGIAVLLQVFQQWTGINAVLFYSASIFEDTGSDISGSD-ATLIIGVTQVTS 299
            |||:.:..||    |.:||.:.....::||.|:.|:...:.:..|....||. |..:.....:.|
Worm   265 SLRQILKDKGCAQALSLAVAINFSVAFSGIVAISFFGTFLLQTIGFSPEGSAVANSLCSFASIVS 329

  Fly   300 TLVAVAIIDKAGRRILLLISGVLMA-VSTALMGVYFQLKENDPASMDNF-GWLPISSICIFIIFF 362
            .|:|...:||.|||.||:.|.:::| ::..:|.:.|..    .::.|:| .|..::...:|...|
Worm   330 ALLAAIAMDKIGRRPLLITSLLVLALINIFMMSLVFLY----DSTKDSFLAWPFLALFVLFTFVF 390

  Fly   363 SIGFGPVPWLVMAELFSEDVKSVAGSIAGTSNWLSAFVVTLLFPILKSSIGPGPTFWIFTAIAVI 427
            |||.||....:.|||......|...|.:.:..:..:|:..:::..|..||| |..|.:|.....|
Worm   391 SIGIGPAAVFIGAELAPPGTISKMQSYSTSVQFAGSFICPIIYLQLVESIG-GFAFMLFIVPLTI 454

  Fly   428 AFFYSLFFVPETKGKTIIEIQDLL 451
            ...|...::||||||:.:||..||
Worm   455 TAAYFYMYLPETKGKSPVEIYGLL 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6484	NP_611234.1	Sugar_tr	14..451	CDD:278511	120/477 (25%)
CG6484	NP_611234.1	MFS	14..436	CDD:119392	112/462 (24%)
K08H10.6	NP_505572.1	MFS_GLUT_Class1_2_like	24..469	CDD:340915	116/468 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D524131at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920