DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6484 and F53H8.3

DIOPT Version :9

Sequence 1:	NP_611234.1	Gene:	CG6484 / 36994	FlyBaseID:	FBgn0034247	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_001359933.1	Gene:	F53H8.3 / 186195	WormBaseID:	WBGene00018779	Length:	509	Species:	Caenorhabditis elegans

Alignment Length:	485	Identity:	124/485 - (25%)
Similarity:	207/485 - (42%)	Gaps:	87/485 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 IAGLSASFGALCMGASIGWSSPVENMIT--VNTEY--------GFPISSSQFGWVSSLLTLGATV 65
            :.|.||.|      .|.|..:|.:.:||  :|..|        ...:|:..:.:|.|.:.:||.
Worm    14 VLGGSAQF------YSYGVVNPAQVVITDWINQTYIDRYKAPLSLTVSNVIWSFVVSSIAIGAI- 71

  Fly    66 ICIPIGFAIDWI-----GRRPTMLALIPPYMVGWVLMLFA----------KNVTMLYFGRFILGM 115
                :|.:...|     |||..|       ....:|.:||          .:..:|.||||:.|:
Worm    72 ----LGASFTRIIGEKYGRRNGM-------FFNGILNVFAALFELVAKRFSSPELLIFGRFVYGI 125

  Fly   116 CGGAFCVTAPMYCTEITATALRGTIGSFFQLLIVSGVLYGYLVG-------------AF-LPLLT 166
            ..|......|||..|||....||..|:..|:.:.....:..|:|             || ||.|.
Worm   126 NMGLSSGLVPMYLMEITPYKYRGPAGTLHQIAVAFSDWFSLLIGLPEVLGDQNNWPLAFALPGLP 190

  Fly   167 INILCAILPVIFAIIHFFMPESPVY-LAMKGRNDDAAKALQWLRGKDADIDDELKEILEESQKQI 230
            ...|..|||        |.||||.| |..|...|.|.|.::.|.||     ::...:.|...:::
Worm   191 ALALVCILP--------FCPESPKYTLGTKHDRDKALKDVELLIGK-----EQAPHMFESIVREV 242

  Fly   231 --DMPQVNILSSLRRPIVLKGLGIAVLLQVFQQWTGINAVLFYSASIFEDTG-SDISGSDATLII 292
              |...........||.:...|.:::::.:.||:||..||..:|..:|.:.| :.:....:||.|
Worm   243 ALDEGDGTFRELFTRPDLRIPLAVSIIVMIAQQFTGCTAVFAFSTDMFLNAGLTPVIARFSTLAI 307

  Fly   293 GVTQVTSTLVAVAIIDKAGRRILLLISGVLMAVSTALMGVYFQLKENDPASMDNFGWL---PISS 354
            |:........:..:|.|.|||.|.|.......|:..|:.::..|:     :.:|..|.   .|.|
Worm   308 GIVYFLFACTSPFLIHKVGRRWLSLFQLASCMVALMLLSLFTFLQ-----NYENIEWARYGTIFS 367

  Fly   355 ICIFIIFFSIGFGPVPWLVMAELFSEDVKSVAGSIAGTSNWLSAFVVTLLFPILKSSIGPGPTFW 419
            :..::..:.:| .|:||::.:|||::..::.|.:::....|..||:|:..:...:..:  |.||.
Worm   368 LVFYMCVYGVG-SPIPWIIASELFTQQFRATAVTVSVFVAWTFAFIVSTSYLPFQQLV--GITFS 429

  Fly   420 IFTAIAVIAFFYSLFFV--PETKGKTIIEI 447
            .|..|..:|.|....:|  |||:.:.::||
Worm   430 YFPFIIGLAVFGIFIYVLLPETRDRPMVEI 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6484	NP_611234.1	Sugar_tr	14..451	CDD:278511	123/482 (26%)
CG6484	NP_611234.1	MFS	14..436	CDD:119392	117/467 (25%)
F53H8.3	NP_001359933.1	MFS_GLUT_Class1_2_like	9..454	CDD:340915	122/478 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910