Protein Alignment CG6484 and SLC22A31

DIOPT Version :10

• Sequence 1: NP_611234.1
• Gene: CG6484 / 36994
• FlyBaseID: FBgn0034247
• Length: 465
• Species: Drosophila melanogaster
• Sequence 2: NP_001371692.1
• Gene: SLC22A31 / 146429
• HGNCID: 27091
• Length: 446
• Species: Homo sapiens
• Alignment Length: 514
• Identity: 104/514 - (20%)
• Similarity: 174/514 - (33%)
• Gaps: 187/514 - (36%)

  Fly    14 LSASFGALCMGASIGWSSPVENMITVNTEYGFPISSSQFGWVSSLLTLGATVICIPIGFAIDWIG 78
            ||.::..:|   ..||..|:|.:            |...||:     ||    |:.:|...|..|
Human     5 LSQNWNLVC---GDGWKVPLEQV------------SHLLGWL-----LG----CVILGAGCDRFG 45

  Fly    79 RR-----------------------PTMLALIPPYMVGWVLMLFAKNVTMLYFGRFIL------- 113
            ||                       ||:|.|  ..:.|..|   |..:..||..|..|
Human    46 RRAVFVASLVLTTGLGASEALAASFPTLLVL--RLLHGGTL---AGALLALYLARLELCDPPHRL 105

  Fly   114 --GMCGGAFCVTAPMYCTEITATA-----LRGTIGSFFQLLIVSGVL---YGYLVGAFLPLLTIN 168
              .|..|.|.|...:....:.|..     |:| :|:     ::||:|   :|:
Human   106 AFSMGAGLFSVVGTLLLPGLAALVQDWRLLQG-LGA-----LMSGLLLLFWGF------------ 152

  Fly   169 ILCAILPVIFAIIHFFMPESPVYLAMKGRNDDAAKALQWLRGKDADI---DDELKE---ILEESQ 227
                  |.:|       ||||.:|...|:...|.|.| |...:.:.:   |..|:|   ..|.:.
Human   153 ------PALF-------PESPCWLLATGQVARARKIL-WRFAEASGVGPGDSSLEENSLATELTM 203

  Fly   228 KQIDMPQVNI---LSSLRRPIVLKG---LGIAVLL-----QVFQQWTGINAVLFYSASIFEDTGS 281
            .....||...   |..||..:..:.   ||.:.|:     ..|::........||.....|
Human   204 LSARSPQPRYHSPLGLLRTRVTWRNGLILGFSSLVGGGIRASFRRSLAPQVPTFYLPYFLE---- 264

  Fly   282 DISGSDATLIIGVTQVTSTLVAVAIIDKAGRRILLLISGVLMAVSTALM--GVYFQLKENDPASM 344
              :|.:|..::       .|:..|  |..|||.:||:..::..:::.|:  |..:.     |
Human   265 --AGLEAAALV-------FLLLTA--DCCGRRPVLLLGTMVTGLASLLLLAGAQYL-----P--- 310

  Fly   345 DNFGWLPISSICIFIIFFSI-------GFGPVPWLVMAELFSEDVKSVA-GSIAGTSNWLSAFVV 401
               ||.        ::|.|:       ....:..|..||:|...::... |.:.|..
Human   311 ---GWT--------VLFLSVLGLLASRAVSALSSLFAAEVFPTVIRGAGLGLVLGAG-------- 356

  Fly   402 TLLFPILKSSIGPGPTFW----------IFTAIAVIAFFYSLFFVPETKGKTIIE-IQD 449
                 .|..:.||..|..          :|.::||:|.. .:..:||::.:.:.: :||
Human   357 -----FLGQAAGPLDTLHGRQGFFLQQVVFASLAVLALL-CVLLLPESRSRGLPQSLQD 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6484	NP_611234.1	MFS_GLUT6_8_Class3_like	10..446	CDD:340916	102/508 (20%)
SLC22A31	NP_001371692.1	MFS	9..383	CDD:475125	95/481 (20%)