DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6484 and slc2a9

DIOPT Version :9

Sequence 1:	NP_611234.1	Gene:	CG6484 / 36994	FlyBaseID:	FBgn0034247	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	XP_002936818.2	Gene:	slc2a9 / 100495427	XenbaseID:	XB-GENE-5883703	Length:	514	Species:	Xenopus tropicalis

Alignment Length:	485	Identity:	129/485 - (26%)
Similarity:	220/485 - (45%)	Gaps:	53/485 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LSASFG-ALCMGASIG-WSSPVENM-----ITVNTEYGFPISSS----QFGWVSSLLTLGATVIC 67
            |.:||| ::..|.::. .:||.|.:     .|.|..||..:..|    .:....|:..||..:..
Frog    26 LLSSFGSSMLYGYNLAVVNSPSEYIKAFYNTTWNQRYGEALEQSPLTLMYSLTVSVFALGGMLGS 90

  Fly    68 IPIGFAIDWIGRRPTMLALIPPYMVGWVLMLFAK---NVTMLYFGRFILGMCGGAFCVTAPMYCT 129
            :.:|..:...||:.|::...|...|...||..::   :..|:..||||.|:..|......|||..
Frog    91 LLVGILVSRFGRKGTIIRSTPLVFVAGGLMGLSRIFSSPEMVIIGRFITGIHSGISLSVVPMYLG 155

  Fly   130 EITATALRGTIGSFFQLLIVSGVLYGYLVG------------AFLPLLTIN--ILCAILPVIFAI 180
            ||:...|||.:|....:.|..||....::|            .||.|:.:.  :...:||
Frog   156 EISPKNLRGLLGLVPSIFICLGVFSAQVLGLPELLGQDETWPLFLSLVVVPTFVQLVLLP----- 215

  Fly   181 IHFFMPESPVYLAM-KGRNDDAAKALQWLRGKDADIDDELKEILEESQKQIDMPQVNILSSLRRP 244
               :.||||.||.: |........||:...| :.|:.|.::|:.||.:....:..|::...|..|
Frog   216 ---WFPESPRYLLIDKSNVHGTIDALRCFLG-EYDVQDVIEEMQEEQKSFSSVDTVSVCQFLSDP 276

  Fly   245 IVLKGLGIAVLLQVFQQWTGINAVLFYSASIFEDTGSDISGSDATLI-IGVTQVTSTLVAVAIID 308
            .:...:...:::.:..|.:||:|:.||:.||||:.|..::....|.: .|..::.:.|:....::
Frog   277 TLFWQILSVIVINIGMQLSGIDAIWFYTNSIFENAGIPMAEIPYTTVGTGAIEIVAGLIGCFTVE 341

  Fly   309 KAGRRILLLISGVLMAVSTA--LMGVYFQLKENDPASMDNFGWLPISSICIFIIFFSIGFGPVPW 371
            |.|||.||:.....|....|  .:.:.||      |.:....::.::.:...|..|.||...:|:
Frog   342 KLGRRPLLIGGFSFMGFCCAGITLALVFQ------ARVPVMRYVSVACVIGIIAGFCIGPAGLPF 400

  Fly   372 LVMAELFSEDVKSVAGSIAGTSNWLSAFVVTLLFPILKSSIGPGPTFWIFTAIAVIAFFYSLFFV 436
            ::..|||::..:..|..:.||.||||.|.|..:||.|:.|.| ...:.:|..|.:....|..:.:
Frog   401 IITGELFTQSHRPAAFIVGGTLNWLSNFTVGFVFPFLQISAG-AFCYMVFCGICLFVAAYVYYII 464

  Fly   437 PETKGKTIIEIQDLLSGGKG-----VKSDD 461
            ||||.:|.:||..:.|..|.     |.:||
Frog   465 PETKNRTFMEISLMFSSSKSPVTHEVTADD 494

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6484	NP_611234.1	Sugar_tr	14..451	CDD:278511	124/468 (26%)
CG6484	NP_611234.1	MFS	14..436	CDD:119392	117/453 (26%)
slc2a9	XP_002936818.2	MFS_GLUT_Class2	30..475	CDD:340990	120/460 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910