Protein Alignment Dcr-2 and rnc

DIOPT Version :10

• Sequence 1: NP_523778.2
• Gene: Dcr-2 / 36993
• FlyBaseID: FBgn0034246
• Length: 1722
• Species: Drosophila melanogaster
• Sequence 2: NP_417062.1
• Gene: rnc / 947033
• ECOCYCID: EG10857
• Length: 226
• Species: Escherichia coli
• Alignment Length: 297
• Identity: 71/297 - (23%)
• Similarity: 124/297 - (41%)
• Gaps: 87/297 - (29%)

  Fly  1430 LINHYYLEKNLGYTFKDRRYLLQALTHPSYPTNRITGSYQELEFIGDAILDFLISAYIFENNTKM 1494
            :||.  |::.|||||..:..|.|||||.|..:..    .:.|||:||:||.::|:..::....::
E. coli     5 VINR--LQRKLGYTFNHQELLQQALTHRSASSKH----NERLEFLGDSILSYVIANALYHRFPRV 63

  Fly  1495 NPGALTDLRSALVNNTTLACICVRHRLHFFILAENAKLSEIISKFVNFQESQGHRVTNYVRILLE 1559
            :.|.::.:|:.||...|||
E. coli    64 DEGDMSRMRATLVRGNTLA---------------------------------------------- 82

  Fly  1560 EADVQPTPLDLDDELDMTELPHANKCISQEAEKGVPPKGEFNMSTNVDVPKALGDVLEALIAAVY 1624
                     :|..|.::.|      |:  ....|....|.|...:      .|.|.:||||..|:
E. coli    83 ---------ELAREFELGE------CL--RLGPGELKSGGFRRES------ILADTVEALIGGVF 124

  Fly  1625 LDCRDLQRTWEVIFNLFEPELQEFT----RKVPINHIRQLVEHKHAK-PVFSSPIVEGET----V 1680
            || .|:|...::|.|.::..|.|.:    :|.|...:::.::.:|.. |.:....|.||.    .
E. coli   125 LD-SDIQTVEKLILNWYQTRLDEISPGDKQKDPKTRLQEYLQGRHLPLPTYLVVQVRGEAHDQEF 188

  Fly  1681 MVSCQFTCMEKTIKVYGFGSNKDQAKLSAAKHALQQL 1717
            .:.||.:.:.:  .|.|.||::.:|:.:||:.||::|
E. coli   189 TIHCQVSGLSE--PVVGTGSSRRKAEQAAAEQALKKL 223

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dcr-2	NP_523778.2	DEXHc_dicer	6..204	CDD:350792
		Dicer_PBD	241..343	CDD:277191
		SF2_C_dicer	360..506	CDD:350189
		Dicer_dimer	571..670	CDD:460900
		PAZ	843..1004	CDD:198017
		RIBOc	1194..1391	CDD:238333
		RIBOc	1448..1649	CDD:238333	44/200 (22%)
		dsrm	1653..1717	CDD:425434	17/68 (25%)
rnc	NP_417062.1	Rnc	6..210	CDD:440336	65/281 (23%)