Protein Alignment Dcr-2 and Mrpl44

DIOPT Version :10

• Sequence 1: NP_523778.2
• Gene: Dcr-2 / 36993
• FlyBaseID: FBgn0034246
• Length: 1722
• Species: Drosophila melanogaster
• Sequence 2: NP_001074679.1
• Gene: Mrpl44 / 69163
• MGIID: 1916413
• Length: 333
• Species: Mus musculus
• Alignment Length: 273
• Identity: 54/273 - (19%)
• Similarity: 99/273 - (36%)
• Gaps: 87/273 - (31%)

  Fly  1522 HFFILAENAKLSEIIS------KFVNFQESQGHRVTNYVRILLEEA-------DVQPTPLDLDDE 1573
            |..:.|..::|.|..|      .|:|         :.|::  .|||       :.:...|:|.|.
Mouse    69 HAEVQAFGSRLQETFSLDLLKTAFIN---------SCYIK--SEEAKRQSLGIEKEAALLNLKDN 122

  Fly  1574 LDMTE--LPHANKCISQEAE---KGVPPKG------------------------EFNMSTNVDVP 1609
            .::.|  |..:::|::|..|   ..:|.:|                        :..:|....||
Mouse   123 QELFEQGLSFSHRCLTQFLEDEFPDLPAEGTESLVSFLTGEAVVCHVARNLAVEQLTLSAEFPVP 187

  Fly  1610 -----KALGDVLEALI-------AAVY--------LDCRDLQRTWEVI--FNLFEPELQEFTRKV 1652
                 :....|:.||:       ||::        :..::|...|.|:  ..|...||::.....
Mouse   188 LPVLRQTFFAVIGALLQSSGPERAALFIRDFLITQMTGKELFEMWTVVNPMGLLVEELKKRNISA 252

  Fly  1653 PINHIRQLVEHKHAKPVF-------SSPIVE--GETVMVSCQFTCMEKTIKVYGFGSNK---DQA 1705
            |.:.:.:......|.|::       ...|.|  ||||:|:.:........|:|||..|:   |.:
Mouse   253 PESRLTRQSGSTTALPLYFVGLYCDRKLIAEGPGETVLVAEEEAARVALRKLYGFTENRRPWDYS 317

  Fly  1706 KLSAAKHALQQLS 1718
            |...:....:|.|
Mouse   318 KPKESPKRAEQTS 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dcr-2	NP_523778.2	DEXHc_dicer	6..204	CDD:350792
		Dicer_PBD	241..343	CDD:277191
		SF2_C_dicer	360..506	CDD:350189
		Dicer_dimer	571..670	CDD:460900
		PAZ	843..1004	CDD:198017
		RIBOc	1194..1391	CDD:238333
		RIBOc	1448..1649	CDD:238333	35/190 (18%)
		dsrm	1653..1717	CDD:425434	17/75 (23%)
Mrpl44	NP_001074679.1	DSRM_MRPL44	225..307	CDD:380703	18/81 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	311..333		4/20 (20%)