back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Dcr-2 and mrpl44

DIOPT Version :10

Sequence 1:	NP_523778.2	Gene:	Dcr-2 / 36993	FlyBaseID:	FBgn0034246	Length:	1722	Species:	Drosophila melanogaster
Sequence 2:	NP_001025431.2	Gene:	mrpl44 / 571210	ZFINID:	ZDB-GENE-050913-59	Length:	332	Species:	Danio rerio

Alignment Length:	389	Identity:	79/389 - (20%)
Similarity:	124/389 - (31%)	Gaps:	138/389 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly  1390 LEYFKICRADIDKPLTQLLNLELGGKK--MRANVNTTEIDGFLINHYYLEKNLGYTFKDRRYLLQ 1452
            |.|..:||..:   |||:..     ||  |:|                      |.|..|:.|
Zfish    15 LHYHHVCRGVM---LTQIRE-----KKRWMKA----------------------YMFVMRKKL-- 47

  Fly  1453 ALTHPSYPTNRIT----GSYQELEFIGDAI-----LDFLISAYI----FENNTKMNPGALTDLRS 1504
            .|..|..|..|..    ..:.|:|..|..:     :|.|.:|::    ..:..:.......|..|
Zfish    48 KLEGPPAPKPRSEQPNFDYHAEVEAFGVRLQESFSVDLLKTAFVNSCYLRSEVERRKALGLDSES 112

  Fly  1505 ALVN---NTTLACICVRHRLHFF--ILAENAKLSEIISKFVNFQES-----QGHRVTNYVRILLE 1559
            |::|   ||.|.    .|..||.  .|::..|     :.|.|..:.     .||...:.|
Zfish   113 AILNLKDNTELR----DHGQHFTTGFLSDWCK-----NSFPNLPDEGVAAIAGHLTGSEV----- 163

  Fly  1560 EADVQPTPLDLDDELDMTELPHANKCISQEAEKGVPPKGEFNMSTNVDVP--------------- 1609
                               :.|..:.::.|         |..||....||
Zfish   164 -------------------ICHVARNLAVE---------ELTMSAEFPVPDHILQGTFFAVIGAL 200

  Fly  1610 -KALGDVLEALIAAVYLDC----RDLQRTWEVIFNLFEPE---LQEFTRKVPINHIRQLVEHKHA 1666
             ::.|.|...|....:|..    :||...|:|:    :|.   ::|.|||.......:|:....|
Zfish   201 EQSSGPVRAGLFIRDFLVTQLIGKDLFDMWKVV----DPMGLLVEELTRKGVALPEPRLIRSAGA 261

  Fly  1667 KPVFSSPIV------------EGETVMVSCQFTCMEKTIKVYGFGSNKDQAKLSAAKHALQQLS 1718
            ..|.....|            .||||:::.:........|:|||..|:.....:|.:..||:.|
Zfish   262 STVLPLYFVGLYSDRKLLAQGPGETVLIAEEEAARVALRKLYGFTENRRPFDFTAPRDQLQKPS 325

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.