| Sequence 1: | NP_523778.2 | Gene: | Dcr-2 / 36993 | FlyBaseID: | FBgn0034246 | Length: | 1722 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_055129.2 | Gene: | DDX58 / 23586 | HGNCID: | 19102 | Length: | 925 | Species: | Homo sapiens |
| Alignment Length: | 595 | Identity: | 148/595 - (24%) |
|---|---|---|---|
| Similarity: | 251/595 - (42%) | Gaps: | 147/595 - (24%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 7 KPRGYQLRL-VDHLTKSNGIVYLPTGSGKTFVAILV----LKRFSQDFDKPIESGGK-RALFMCN 65
Fly 66 TVELARQQAMAVRRCTNFKVGFYVGEQGVDDWTRGMWSDE--IKKNQVLVGTAQVFLDMVTQ-TY 127
Fly 128 VALSSLSVVIIDECHHGTGHHPFREFMRLFTIANQT------KLPRVVGLTGVLIKGNEITNVAT 186
Fly 187 KLKELEITYRGNIITVSDTKEMENVMLY-----ATKPTEVMVSFPHQ----EQVLTVTRLISAEI 242
Fly 243 E-----KF-YVSLDLMNIGVQPIRRSKSLQCLRDPSKKSFVKQLFNDFLYQMKEYGIYAASIAII 301
Fly 302 SL---IVEFDIKRRQAETLSVKLM---------HRTALTLCEKIRHLLVQKLQD-MTY-DDDDDN 352
Fly 353 VNT---EEVIMNFSTPKVQRF------LMSLKVSFADKDPK--DIC--------------CLVFV 392
Fly 393 ERRYTCKCIYGLLLNYIQSTPELRNVLTPQFMVGRNNISPDFESVLERKWQKSAIQQFR-DGNAN 456
Fly 457 LMICSSVLEEGIDVQACNHVFILDPVKTFNMYVQSKGRARTTEAKFVLFTADK---EREKTIQQI 518
Fly 519 YQYR-KAHND 527 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Dcr-2 | NP_523778.2 | MPH1 | 6..542 | CDD:224036 | 148/595 (25%) |
| DEXDc | 22..173 | CDD:238005 | 47/164 (29%) | ||
| Dicer_PBD | 241..343 | CDD:277191 | 24/119 (20%) | ||
| HELICc | <438..495 | CDD:197757 | 19/57 (33%) | ||
| Dicer_dimer | 572..665 | CDD:281376 | |||
| PAZ | 843..1004 | CDD:198017 | |||
| RIBOc | 1194..1391 | CDD:238333 | |||
| Rnc | 1433..1719 | CDD:223644 | |||
| RIBOc | 1448..1649 | CDD:238333 | |||
| dsrm | 1653..1717 | CDD:278464 | |||
| DDX58 | NP_055129.2 | DD | 2..92 | CDD:326335 | |
| CARD_RIG-I_r2 | 100..189 | CDD:260076 | |||
| Interaction with ZC3HAV1. /evidence=ECO:0000269|PubMed:21102435 | 218..925 | 148/595 (25%) | |||
| helicase_insert_domain | 243..771 | CDD:327377 | 147/594 (25%) | ||
| DECH box | 372..375 | 2/2 (100%) | |||
| Mediates interaction with RNF135. /evidence=ECO:0000269|PubMed:23950712 | 735..925 | 11/33 (33%) | |||
| RIG-I_C | 805..918 | CDD:276943 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D1337630at2759 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.920 | |||||