| Sequence 1: | NP_523778.2 | Gene: | Dcr-2 / 36993 | FlyBaseID: | FBgn0034246 | Length: | 1722 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_766277.3 | Gene: | Ddx58 / 230073 | MGIID: | 2442858 | Length: | 926 | Species: | Mus musculus |
| Alignment Length: | 591 | Identity: | 142/591 - (24%) |
|---|---|---|---|
| Similarity: | 253/591 - (42%) | Gaps: | 123/591 - (20%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 6 IKPRGYQLRLVDHLTK-SNGIVYLPTGSGKTFVAILV----LKRFSQDFDKPIESGGKRALFMCN 65
Fly 66 TVELARQQAMAVRRCTNFKVGFYVGEQGVDDWTRGMWSDE------IKKNQVLVGTAQVFLDMVT 124
Fly 125 QTYV-ALSSLSVVIIDECHHGTGHHPFREFMRLFTI----ANQTKLPRVVGLTGVLIKGNEIT-- 182
Fly 183 ----NVATKLKELEITYRGNIITVSD-TKEMENVMLYATKPTEVMVSFPHQEQVLTVTRL----- 237
Fly 238 -----ISAEIEKFYVSLDLMNIGVQP-------IRRSKSLQCLRDPSKKSFV-KQLFNDFLY--Q 287
Fly 288 MKEYGIYAASIAIISLIVEFDIKRRQAETLSVKLMH--------RTALTLCEKIRHLLVQKLQDM 344
Fly 345 TYDDDDDNVNTEEVIMNFSTPKVQRFLMSLKVSFADK-DPKDICCLVFVERRYTCKCIYGLLLNY 408
Fly 409 IQSTPELRNVLTPQFMVGRNNISPDFESVLERKWQKSAIQQFR-DGNANLMICSSVLEEGIDVQA 472
Fly 473 CNHVFILDPVKTFNMYVQSKGRARTTEAKFVLFTADK---EREKTIQQIYQYRKAHNDIAEYLKD 534
Fly 535 RVLEKT 540 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Dcr-2 | NP_523778.2 | MPH1 | 6..542 | CDD:224036 | 142/591 (24%) |
| DEXDc | 22..173 | CDD:238005 | 47/165 (28%) | ||
| Dicer_PBD | 241..343 | CDD:277191 | 23/119 (19%) | ||
| HELICc | <438..495 | CDD:197757 | 20/57 (35%) | ||
| Dicer_dimer | 572..665 | CDD:281376 | |||
| PAZ | 843..1004 | CDD:198017 | |||
| RIBOc | 1194..1391 | CDD:238333 | |||
| Rnc | 1433..1719 | CDD:223644 | |||
| RIBOc | 1448..1649 | CDD:238333 | |||
| dsrm | 1653..1717 | CDD:278464 | |||
| Ddx58 | NP_766277.3 | CARD_RIG-I_r1 | 2..92 | CDD:260075 | |
| CARD_RIG-I_r2 | 100..188 | CDD:260076 | |||
| Interaction with ZC3HAV1. /evidence=ECO:0000250 | 219..926 | 142/591 (24%) | |||
| MPH1 | 242..807 | CDD:224036 | 142/591 (24%) | ||
| DEXDc | 259..411 | CDD:238005 | 47/165 (28%) | ||
| DECH box | 373..376 | 2/2 (100%) | |||
| MDA5_ID | 470..605 | CDD:277189 | 25/147 (17%) | ||
| Helicase_C | 614..734 | CDD:278689 | 36/129 (28%) | ||
| Mediates interaction with RNF135. /evidence=ECO:0000250|UniProtKB:O95786 | 736..926 | 8/45 (18%) | |||
| RIG-I_C-RD | 808..923 | CDD:288493 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D1337630at2759 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.920 | |||||