Protein Alignment Dcr-2 and mRpL44

DIOPT Version :10

• Sequence 1: NP_523778.2
• Gene: Dcr-2 / 36993
• FlyBaseID: FBgn0034246
• Length: 1722
• Species: Drosophila melanogaster
• Sequence 2: XP_321167.5
• Gene: mRpL44 / 1281227
• VectorBaseID: AGAMI1_006950
• Length: 329
• Species: Anopheles gambiae
• Alignment Length: 313
• Identity: 63/313 - (20%)
• Similarity: 101/313 - (32%)
• Gaps: 120/313 - (38%)

  Fly  1438 KNLGYTFKDRRYLLQALTHPSY---PTNR---------ITGSYQELEFI--GDAILDFLISAYIF 1488
            |.|..:| |...|.||.||.|:   .|.:         :.|.:...|.|  |:.::...:.|::.
Mosquito    68 KRLQESF-DANVLQQAFTHQSFIEQETRKQAAVGIEQPVLGVHDNRELIAQGEQLVAEYVEAFLL 131

  Fly  1489 ENNTKMNPGALTDLRSALVNNTTLACICVRHRLHFFILA-----ENAKLSEIISKFV-NFQESQG 1547
            ....::....:..:|.||.:...||.:.........|:|     ::|.|:..:...| ..|.|.|
Mosquito   132 TALPRLPRQFIASVREALTSEAQLAHVSAHLGTKDIIMAAEFPIDDALLASTLKAIVAALQRSSG 196

  Fly  1548 -HRVTNYVRILLEEADVQPTPLDLDDELDMTELPHANKCISQEAEKGVPPKGEFNMSTNVDVPKA 1611
             .|...:||..|                          |            |:.|..
Mosquito   197 DERCFLFVRDFL--------------------------C------------GQLNQR-------- 215

  Fly  1612 LGDVLEALIAAVYLDCRDLQRTWEVIFNLFEPELQEFTRKVPINHIRQLVEHKHAKPVFSSPIVE 1676
              |:.|      ||:..|..||           |||:.:           |...|.|   .|.:.
Mosquito   216 --DLYE------YLEIADPLRT-----------LQEYCK-----------ERGLADP---EPRLI 247

  Fly  1677 G----ETVMVSCQFTCMEKTIKVY--------GFGSNKDQAKLSAAKHALQQL 1717
            |    .|::.:.|       :.:|        |:|.|:..|...||:..|:||
Mosquito   248 GNVGRNTLLAAHQ-------VGIYSDRKLLGTGYGENQTVAVEEAARDCLRQL 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dcr-2	NP_523778.2	DEXHc_dicer	6..204	CDD:350792
		Dicer_PBD	241..343	CDD:277191
		SF2_C_dicer	360..506	CDD:350189
		Dicer_dimer	571..670	CDD:460900
		PAZ	843..1004	CDD:198017
		RIBOc	1194..1391	CDD:238333
		RIBOc	1448..1649	CDD:238333	42/221 (19%)
		dsrm	1653..1717	CDD:425434	15/75 (20%)
mRpL44	XP_321167.5	None