DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab4 and Rab14

DIOPT Version :9

Sequence 1:	NP_523777.1	Gene:	Rab4 / 36992	FlyBaseID:	FBgn0016701	Length:	213	Species:	Drosophila melanogaster
Sequence 2:	NP_080973.1	Gene:	Rab14 / 68365	MGIID:	1915615	Length:	215	Species:	Mus musculus

Alignment Length:	208	Identity:	122/208 - (58%)
Similarity:	152/208 - (73%)	Gaps:	1/208 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 YDYLFKFLIIGSAGSGKSCLLHHFIESKFKDDSSHTIGVEFGSRIVNVGGKSVKLQIWDTAGQER 69
            |.|:||::|||..|.|||||||.|.|.||..|..||||||||:||:.|.|:.:||||||||||||
Mouse     8 YSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQER 72

  Fly    70 FRSVTRSYYRGAAGALLVYDATSRDSFNALTNWLNDARTLASPNIVILLVGNKKDLEEARDVTFL 134
            ||:|||||||||||||:|||.|.|.::|.|::||.|||.|.:||.||:|:|||.|||..||||:.
Mouse    73 FRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADLEAQRDVTYE 137

  Fly   135 EASTFAQENELIFLETSAKTGENVEEAFLKCSKTILAKIETGELDPERIGSGIQYGGAALRNLQ- 198
            ||..||:||.|:|||.|||||||||:|||:.:|.|...|:.|.||.....||:|:..:|.:..:
Mouse   138 EAKQFAEENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQDGSLDLNAAESGVQHKPSAPQGGRL 202

  Fly   199 TRQRSINKPDCTC 211
            |.:....:..|.|
Mouse   203 TSEPQPQREGCGC 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab4	NP_523777.1	Rab4	9..169	CDD:206696	108/159 (68%)
Rab14	NP_080973.1	Rab14	10..175	CDD:133322	110/164 (67%)
		Effector region. /evidence=ECO:0000250	40..48		5/7 (71%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	188..215		6/26 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001311
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X808
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910