Protein Alignment Rab4 and Rab5a

DIOPT Version :10

• Sequence 1: NP_523777.1
• Gene: Rab4 / 36992
• FlyBaseID: FBgn0016701
• Length: 213
• Species: Drosophila melanogaster
• Sequence 2: NP_073183.1
• Gene: Rab5a / 64633
• RGDID: 620936
• Length: 215
• Species: Rattus norvegicus
• Alignment Length: 182
• Identity: 78/182 - (42%)
• Similarity: 112/182 - (61%)
• Gaps: 6/182 - (3%)

  Fly     9 FKFLIIGSAGSGKSCLLHHFIESKFKDDSSHTIGVEFGSRIVNVGGKSVKLQIWDTAGQERFRSV 73
            ||.:::|.:..|||.|:..|::.:|.:....|||..|.::.|.:...:||.:|||||||||:.|:
  Rat    21 FKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSL 85

  Fly    74 TRSYYRGAAGALLVYDATSRDSFNALTNWLNDARTLASPNIVILLVGNKKDLEEARDVTFLEAST 138
            ...|||||..|::|||.|:.:||:...||:.:.:..|||||||.|.|||.||...|.|.|.||.:
  Rat    86 APMYYRGAQAAIVVYDITNEESFSRAKNWVKELQRQASPNIVIALSGNKADLANKRAVDFQEAQS 150

  Fly   139 FAQENELIFLETSAKTGENVEEAFLKCSKTILAKIETGELDPERIGSGIQYG 190
            :|.:|.|:|:||||||..||.|.|:..:|    |:...|  |:..|:....|
  Rat   151 YADDNSLLFMETSAKTSMNVNEIFMAIAK----KLPKNE--PQNPGANSARG 196

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab4	NP_523777.1	Rab4	9..169	CDD:206696	73/159 (46%)
Rab5a	NP_073183.1	Rab5_related	20..182	CDD:206653	74/164 (45%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P20339	44..56		4/11 (36%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P20339	77..93		9/15 (60%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	181..215		4/18 (22%)