Protein Alignment Rab4 and Rab2a

DIOPT Version :10

• Sequence 1: NP_523777.1
• Gene: Rab4 / 36992
• FlyBaseID: FBgn0016701
• Length: 213
• Species: Drosophila melanogaster
• Sequence 2: NP_001398756.1
• Gene: Rab2a / 59021
• MGIID: 1928750
• Length: 216
• Species: Mus musculus
• Alignment Length: 209
• Identity: 104/209 - (49%)
• Similarity: 139/209 - (66%)
• Gaps: 9/209 - (4%)

  Fly     5 YDYLFKFLIIGSAGSGKSCLLHHFIESKFKDDSSHTIGVEFGSRIVNVGGKSVKLQIWDTAGQER 69
            |.||||::|||..|.||||||..|.:.:|:.....|||||||:|::.:.||.:|||||||||||.
Mouse     3 YAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQES 67

  Fly    70 FRSVTRSYYRGAAGALLVYDATSRDSFNALTNWLNDARTLASPNIVILLVGNKKDLEEARDVTFL 134
            |||:||||||||||||||||.|.||:||.||.||.|||..::.|:||:|:|||.|||..|:|...
Mouse    68 FRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKE 132

  Fly   135 EASTFAQENELIFLETSAKTGENVEEAFLKCSKTILAKIETGELDPERIGSGIQYGGAALRNLQT 199
            |...||:|:.|||:||||||..||||        ::....|.:::..:...|...|| :::.::.
Mouse   133 EGEAFAREHGLIFMETSAKTASNVEE--------VMNAESTVQMNHCQDAGGCCMGG-SVKTIKR 188

  Fly   200 RQRSINKPDCTCRV 213
            :...:....|:..|
Mouse   189 QHLRVYLSHCSIAV 202

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab4	NP_523777.1	Rab4	9..169	CDD:206696	95/159 (60%)
Rab2a	NP_001398756.1	Required for interaction with PRKCI. /evidence=ECO:0000250	2..19		9/15 (60%)
		Rab2	3..158	CDD:206658	96/154 (62%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P61106	37..42		3/4 (75%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P61106	63..72		7/8 (88%)