Protein Alignment Rab4 and RAB13

DIOPT Version :10

• Sequence 1: NP_523777.1
• Gene: Rab4 / 36992
• FlyBaseID: FBgn0016701
• Length: 213
• Species: Drosophila melanogaster
• Sequence 2: NP_002861.1
• Gene: RAB13 / 5872
• HGNCID: 9762
• Length: 203
• Species: Homo sapiens
• Alignment Length: 210
• Identity: 89/210 - (42%)
• Similarity: 124/210 - (59%)
• Gaps: 23/210 - (10%)

  Fly     1 MSETYDYLFKFLIIGSAGSGKSCLLHHFIESKFKDDSSHTIGVEFGSRIVNVGGKSVKLQIWDTA 65
            |::.||:|||.|:||.:|.||:||:..|.|..|.:....|||::|..|.|::.||.:|||:||||
Human     1 MAKAYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKIKLQVWDTA 65

  Fly    66 GQERFRSVTRSYYRGAAGALLVYDATSRDSFNALTNWLNDARTLASPNIVILLVGNKKDLEEARD 130
            |||||:::|.:|||||.|.:||||.|...||..:.||:...:..||..:..||:|||.|:|..|.
Human    66 GQERFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERLLLGNKCDMEAKRK 130

  Fly   131 VTFLEASTFAQENELIFLETSAKTGENVEEAFLKCSKTILAKIETGELDPERIGSGIQYGGAALR 195
            |...:|...|:|:.:.|.|||||:..||:|||...::.||.|  :|   ..|.|:|
Human   131 VQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDILLK--SG---GRRSGNG--------- 181

  Fly   196 NLQTRQRSINKPDCT 210
                     |||..|
Human   182 ---------NKPPST 187

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab4	NP_523777.1	Rab4	9..169	CDD:206696	74/159 (47%)
RAB13	NP_002861.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	78/165 (47%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	31..45		4/13 (31%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	63..80		11/16 (69%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	173..203		8/36 (22%)