Protein Alignment Rab4 and RAB5B

DIOPT Version :10

• Sequence 1: NP_523777.1
• Gene: Rab4 / 36992
• FlyBaseID: FBgn0016701
• Length: 213
• Species: Drosophila melanogaster
• Sequence 2: NP_001401387.1
• Gene: RAB5B / 5869
• HGNCID: 9784
• Length: 296
• Species: Homo sapiens
• Alignment Length: 207
• Identity: 82/207 - (39%)
• Similarity: 121/207 - (58%)
• Gaps: 21/207 - (10%)

  Fly     9 FKFLIIGSAGSGKSCLLHHFIESKFKDDSSHTIGVEFGSRIVNVGGKSVKLQIWDTAGQERFRSV 73
            ||.:::|.:..|||.|:..|::.:|.:....|||..|.::.|.:...:||.:|||||||||:.|:
Human   102 FKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLDDTTVKFEIWDTAGQERYHSL 166

  Fly    74 TRSYYRGAAGALLVYDATSRDSFNALTNWLNDARTLASPNIVILLVGNKKDLEEARDVTFLEAST 138
            ...|||||..|::|||.|::::|.....|:.:.:..|||:|||.|.|||.||...|.|.:.||..
Human   167 APMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQASPSIVIALAGNKADLANKRMVEYEEAQA 231

  Fly   139 FAQENELIFLETSAKTGENVEEAFLKCSKTILAKIETGELDPERIGSGIQYGGAALRNL------ 197
            :|.:|.|:|:||||||..||.:.||..:|    |:...|  |:.:      ||||.|:.
Human   232 YADDNSLLFMETSAKTAMNVNDLFLAIAK----KLPKSE--PQNL------GGAAGRSRGVDLHE 284

  Fly   198 QTRQRSINKPDC 209
            |::|   ||..|
Human   285 QSQQ---NKSQC 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab4	NP_523777.1	Rab4	9..169	CDD:206696	69/159 (43%)
RAB5B	NP_001401387.1	Rab5_related	101..263	CDD:206653	70/164 (43%)