Protein Alignment Rab4 and RAB4A

DIOPT Version :10

• Sequence 1: NP_523777.1
• Gene: Rab4 / 36992
• FlyBaseID: FBgn0016701
• Length: 213
• Species: Drosophila melanogaster
• Sequence 2: NP_004569.2
• Gene: RAB4A / 5867
• HGNCID: 9781
• Length: 218
• Species: Homo sapiens
• Alignment Length: 213
• Identity: 165/213 - (77%)
• Similarity: 190/213 - (89%)
• Gaps: 2/213 - (0%)

  Fly     1 MSETYDYLFKFLIIGSAGSGKSCLLHHFIESKFKDDSSHTIGVEFGSRIVNVGGKSVKLQIWDTA 65
            ||||||:|||||:||:||:|||||||.|||.||||||:|||||||||:|:|||||.|||||||||
Human     6 MSETYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGVEFGSKIINVGGKYVKLQIWDTA 70

  Fly    66 GQERFRSVTRSYYRGAAGALLVYDATSRDSFNALTNWLNDARTLASPNIVILLVGNKKDLEEARD 130
            ||||||||||||||||||||||||.|||:::|||||||.|||.|||.||||:|.||||||:..|:
Human    71 GQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVIILCGNKKDLDADRE 135

  Fly   131 VTFLEASTFAQENELIFLETSAKTGENVEEAFLKCSKTILAKIETGELDPERIGSGIQYGGAALR 195
            |||||||.|||||||:||||||.|||||||||::|::.||.|||:|||||||:|||||||.||||
Human   136 VTFLEASRFAQENELMFLETSALTGENVEEAFVQCARKILNKIESGELDPERMGSGIQYGDAALR 200

  Fly   196 NLQT--RQRSINKPDCTC 211
            .|::  |.::.|..:|.|
Human   201 QLRSPRRAQAPNAQECGC 218

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab4	NP_523777.1	Rab4	9..169	CDD:206696	130/159 (82%)
RAB4A	NP_004569.2	Rab4	14..174	CDD:206696	130/159 (82%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P61106	44..49		4/4 (100%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P61106	70..79		8/8 (100%)