DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Rab4 and Rab18

DIOPT Version :9

Sequence 1:NP_523777.1 Gene:Rab4 / 36992 FlyBaseID:FBgn0016701 Length:213 Species:Drosophila melanogaster
Sequence 2:NP_524744.2 Gene:Rab18 / 44360 FlyBaseID:FBgn0015794 Length:197 Species:Drosophila melanogaster


Alignment Length:173 Identity:77/173 - (44%)
Similarity:111/173 - (64%) Gaps:7/173 - (4%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 DYLFKFLIIGSAGSGKSCLLHHFIESKFKDDSSHTIGVEFGSRIVNVGGKSVKLQIWDTAGQERF 70
            |...|.|:||.:|.|||.|:..|:|:||..:...|||::|.|:::.|.|...|:.:|||||.|||
  Fly     3 DRAIKLLVIGESGVGKSSLIRRFVENKFDQNHDVTIGMDFKSKVMQVDGIDYKVALWDTAGAERF 67

  Fly    71 RSVTRSYYRGAAGALLVYDATSRDSFNALTNWLNDARTLA-SPNIVILLVGNKKDLEEARDVTFL 134
            ||:|.|:||.|.||:||||.|||||...|..||.:..:.: :|||.|::||||  ::|.|.|...
  Fly    68 RSLTPSFYRKALGAILVYDITSRDSLVKLETWLAELDSYSDNPNIAIIVVGNK--IDEERVVDRE 130

  Fly   135 EASTFAQENELIFLETSAKTGENVEEAFLKCSKTILAKIETGE 177
            |...||:::..:|:|||||..:.|.:.|    |.::.||.:.|
  Fly   131 EGRKFARKHRALFIETSAKCDQFVSDVF----KDVVEKIVSSE 169

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rab4NP_523777.1 Rab4 9..169 CDD:206696 73/160 (46%)
Rab18NP_524744.2 RAB 6..166 CDD:197555 74/165 (45%)
Rab18 6..165 CDD:206656 73/164 (45%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45454541
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.840

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