DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab4 and Rab21

DIOPT Version :9

Sequence 1:	NP_523777.1	Gene:	Rab4 / 36992	FlyBaseID:	FBgn0016701	Length:	213	Species:	Drosophila melanogaster
Sequence 2:	NP_001036321.2	Gene:	Rab21 / 3355163	FlyBaseID:	FBgn0039966	Length:	222	Species:	Drosophila melanogaster

Alignment Length:	178	Identity:	70/178 - (39%)
Similarity:	106/178 - (59%)	Gaps:	3/178 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 FKFLIIGSAGSGKSCLLHHFIESKFKDDSSHTIGVEFGSRIVNV-GGKSVKLQIWDTAGQERFRS 72
            ||.:::|....||:.|:..::|.:|......|:...|.||.::: .|:..:|.||||||||||.:
  Fly    14 FKAVLLGEGCVGKTSLVLRYMEDRFNAQHLSTLQASFVSRKMSLEDGRRAQLNIWDTAGQERFHA 78

  Fly    73 VTRSYYRGAAGALLVYDATSRDSFNALTNWLNDARTLASPNIVILLVGNKKDLEEARDVTFLEAS 137
            :...||||:.|||||||.|.||||..:.:|:.:.|.:....|.:::||||.||||.|.||..||.
  Fly    79 LGPIYYRGSDGALLVYDITDRDSFQKVKSWVRELRQMRGTEIALIIVGNKTDLEEQRAVTHDEAL 143

  Fly   138 TFAQENELIFLETSAKTGENVEEAFLKCSKTILAKIETGELD--PERI 183
            .:|:.....::|||||..|.|.|.|...::.:|.::...:.|  |.|:
  Fly   144 QYARTVGAQYVETSAKENEGVAELFELLTQLMLEQLSQRQPDASPLRL 191

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab4	NP_523777.1	Rab4	9..169	CDD:206696	66/160 (41%)
Rab21	NP_001036321.2	Rab21	14..176	CDD:133323	66/161 (41%)
Rab21	NP_001036321.2	Ras	15..177	CDD:278499	65/161 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454549
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840