Protein Alignment Rab4 and Rab18

DIOPT Version :10

• Sequence 1: NP_523777.1
• Gene: Rab4 / 36992
• FlyBaseID: FBgn0016701
• Length: 213
• Species: Drosophila melanogaster
• Sequence 2: NP_001012486.1
• Gene: Rab18 / 307039
• RGDID: 1308905
• Length: 206
• Species: Rattus norvegicus
• Alignment Length: 202
• Identity: 90/202 - (44%)
• Similarity: 122/202 - (60%)
• Gaps: 13/202 - (6%)

  Fly     1 MSETYDYLFKFLIIGSAGSGKSCLLHHFIESKFKDDSSHTIGVEFGSRIVNVGGKSVKLQIWDTA 65
            |.|......|.||||.:|.|||.||..|.:..|..:.:.||||:|..:.::|.|...||.|||||
  Rat     1 MDEDVLTTLKILIIGESGVGKSSLLLRFTDDTFDPELAATIGVDFKVKTISVDGNKAKLAIWDTA 65

  Fly    66 GQERFRSVTRSYYRGAAGALLVYDATSRDSFNALTNWLNDARTLASPN-IVILLVGNKKDLEEAR 129
            ||||||::|.||||||.|.:||||.|.||:|..|.||||:..|..:.| ||.:|||||.| :|.|
  Rat    66 GQERFRTLTPSYYRGAQGVILVYDVTRRDTFVKLDNWLNELETYCTRNDIVNMLVGNKID-KENR 129

  Fly   130 DVTFLEASTFAQENELIFLETSAKTGENVEEAFLKCSKTILAKIET-GELDPERIGSGIQ----- 188
            :|...|...||:::.::|:|.||||.:.|:.||.:..:.|   |:| |..:.|....|::
  Rat   130 EVDRNEGLKFARKHSMLFIEASAKTCDGVQCAFEELVEKI---IQTPGLWESENQNKGVKLSPRE 191

  Fly   189 --YGGAA 193
              :||.|
  Rat   192 ESHGGGA 198

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab4	NP_523777.1	Rab4	9..169	CDD:206696	79/160 (49%)
Rab18	NP_001012486.1	Rab18	9..169	CDD:206656	79/160 (49%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	31..45		5/13 (38%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	63..80		13/16 (81%)