Protein Alignment Rab4 and Rab39

DIOPT Version :10

• Sequence 1: NP_523777.1
• Gene: Rab4 / 36992
• FlyBaseID: FBgn0016701
• Length: 213
• Species: Drosophila melanogaster
• Sequence 2: NP_780771.1
• Gene: Rab39 / 270160
• MGIID: 2442855
• Length: 217
• Species: Mus musculus
• Alignment Length: 219
• Identity: 88/219 - (40%)
• Similarity: 131/219 - (59%)
• Gaps: 10/219 - (4%)

  Fly     1 MSETYDYLFKFLIIGSAGSGKSCLLHHFIESKFKDDSS----HTIGVEFGSRIVNV-GGKSVKLQ 60
            |...:.|.|:.::||.:..|||||||.|.:.:|....|    .|:||:|.||::.: .||.:|||
Mouse     1 METIWIYQFRLIVIGDSTVGKSCLLHRFTQGRFPGLHSPACDPTVGVDFFSRLLEIEPGKRIKLQ 65

  Fly    61 IWDTAGQERFRSVTRSYYRGAAGALLVYDATSRDSFNALTNWLNDARTLASP-NIVILLVGNKKD 124
            :|||||||||||:||||||.:.|..||:|.|:|.||..:.:||.:|:....| .||.||||:|.|
Mouse    66 LWDTAGQERFRSITRSYYRNSVGGFLVFDITNRRSFEHVKDWLEEAKMHVQPFQIVFLLVGHKCD 130

  Fly   125 LEEARDVTFLEASTFAQENELIFLETSAKTGENVEEAFLKCSKTILAKIETGELDPERIGSGIQY 189
            |...|.|:..||...:.:..:.::|||||...||||:|...::.|...|:.||:..:....|::
Mouse   131 LASQRQVSREEAERLSTDCGMKYIETSAKDATNVEESFTILTRDIYELIKKGEICIQDGWEGVK- 194

  Fly   190 GGAALRNLQTRQRSINKP--DCTC 211
            .|.....:.:.:.:: ||  :|.|
Mouse   195 SGFVPNTVHSSEEAV-KPRKECFC 217

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab4	NP_523777.1	Rab4	9..169	CDD:206696	76/165 (46%)
Rab39	NP_780771.1	Rab39	7..217	CDD:133311	86/211 (41%)
		Switch-I. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	39..47		1/7 (14%)
		Switch-II. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	71..87		13/15 (87%)