Protein Alignment Rab4 and Rab7

DIOPT Version :10

• Sequence 1: NP_523777.1
• Gene: Rab4 / 36992
• FlyBaseID: FBgn0016701
• Length: 213
• Species: Drosophila melanogaster
• Sequence 2: NP_033031.2
• Gene: Rab7 / 19349
• MGIID: 105068
• Length: 207
• Species: Mus musculus
• Alignment Length: 219
• Identity: 72/219 - (32%)
• Similarity: 115/219 - (52%)
• Gaps: 20/219 - (9%)

  Fly     1 MSETYDYLFKFLIIGSAGSGKSCLLHHFIESKFKDDSSHTIGVEFGSRIVNVGGKSVKLQIWDTA 65
            |:.....|.|.:|:|.:|.||:.|::.::..||.:....|||.:|.::.|.|..:.|.:||||||
Mouse     1 MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTA 65

  Fly    66 GQERFRSVTRSYYRGAAGALLVYDATSRDSFNALTNWLNDARTLASP----NIVILLVGNKKDLE 126
            |||||:|:..::||||...:||:|.|:.::|..|.:|.::....|||    |...:::|||.|||
Mouse    66 GQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLE 130

  Fly   127 EARDVTFLEASTFAQENELIFLETSAKTGENVEEAFLKCSKTIL---AKIETGELDPERIGSGIQ 188
            ..:..|....:....:|.:.:.|||||...|||:||...::..|   .::|.....||.|
Mouse   131 NRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPEPI----- 190

  Fly   189 YGGAALRNLQTRQRS-INKPDCTC 211
                   .|....|: .:...|:|
Mouse   191 -------KLDKNDRAKASAESCSC 207

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab4	NP_523777.1	Rab4	9..169	CDD:206696	61/163 (37%)
Rab7	NP_033031.2	Rab7	9..179	CDD:206655	62/169 (37%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P51149	28..41		2/12 (17%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P51149	67..82		8/14 (57%)