DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rab4 and rab-14

DIOPT Version :9

Sequence 1:	NP_523777.1	Gene:	Rab4 / 36992	FlyBaseID:	FBgn0016701	Length:	213	Species:	Drosophila melanogaster
Sequence 2:	NP_510572.1	Gene:	rab-14 / 181649	WormBaseID:	WBGene00004276	Length:	210	Species:	Caenorhabditis elegans

Alignment Length:	207	Identity:	119/207 - (57%)
Similarity:	147/207 - (71%)	Gaps:	4/207 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 YDYLFKFLIIGSAGSGKSCLLHHFIESKFKDDSSHTIGVEFGSRIVNVGGKSVKLQIWDTAGQER 69
            |.|:||::|||..|.|||||||.|.|.||..|..||||||||:||:.|.|:.:||||||||||||
Worm     8 YSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQER 72

  Fly    70 FRSVTRSYYRGAAGALLVYDATSRDSFNALTNWLNDARTLASPNIVILLVGNKKDLEEARDVTFL 134
            ||:|||||||||||||:|||.|.|.::|.|::||.||::|.:||..|.|:|||.|||:.|||.:.
Worm    73 FRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLADAKSLTNPNTAIFLIGNKADLEDQRDVPYE 137

  Fly   135 EASTFAQENELIFLETSAKTGENVEEAFLKCSKTILAKIETGELDPERIGSGIQYGGAALRNLQT 199
            ||..||:||.|.|||.|||||.|||:|||:.:|.|...|:.|.||.....:|:|    ..:||..
Worm   138 EAKAFAEENGLTFLECSAKTGSNVEDAFLETAKQIYQNIQDGSLDLNAADTGVQ----PKQNLPR 198

  Fly   200 RQRSINKPDCTC 211
            ...:..|.||.|
Worm   199 AAENNGKKDCNC 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab4	NP_523777.1	Rab4	9..169	CDD:206696	104/159 (65%)
rab-14	NP_510572.1	Rab14	10..175	CDD:133322	106/164 (65%)
rab-14	NP_510572.1	RAB	12..175	CDD:197555	105/162 (65%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1146851at2759
OrthoFinder	1	1.000	-	-		FOG0001311
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X808
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920