Protein Alignment Rab4 and Rab8a

DIOPT Version :10

• Sequence 1: NP_523777.1
• Gene: Rab4 / 36992
• FlyBaseID: FBgn0016701
• Length: 213
• Species: Drosophila melanogaster
• Sequence 2: NP_446450.2
• Gene: Rab8a / 117103
• RGDID: 621144
• Length: 207
• Species: Rattus norvegicus
• Alignment Length: 174
• Identity: 79/174 - (45%)
• Similarity: 114/174 - (65%)
• Gaps: 0/174 - (0%)

  Fly     1 MSETYDYLFKFLIIGSAGSGKSCLLHHFIESKFKDDSSHTIGVEFGSRIVNVGGKSVKLQIWDTA 65
            |::|||||||.|:||.:|.||:|:|..|.|..|......|||::|..|.:.:.||.:||||||||
  Rat     1 MAKTYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTA 65

  Fly    66 GQERFRSVTRSYYRGAAGALLVYDATSRDSFNALTNWLNDARTLASPNIVILLVGNKKDLEEARD 130
            ||||||::|.:|||||.|.:||||.|:..||:.:.||:.:....||.::..:::|||.|:.:.|.
  Rat    66 GQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNKCDVNDKRQ 130

  Fly   131 VTFLEASTFAQENELIFLETSAKTGENVEEAFLKCSKTILAKIE 174
            |:.......|.:..:.|:|||||...|||.||...::.|.||::
  Rat   131 VSKERGEKLALDYGIKFMETSAKANINVENAFFTLARDIKAKMD 174

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab4	NP_523777.1	Rab4	9..169	CDD:206696	70/159 (44%)
Rab8a	NP_446450.2	Rab8_Rab10_Rab13_like	6..172	CDD:206659	74/165 (45%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	31..45		4/13 (31%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	63..80		12/16 (75%)