Protein Alignment POSH and BEM1

DIOPT Version :9

• Sequence 1: NP_523776.1
• Gene: POSH / 36990
• FlyBaseID: FBgn0040294
• Length: 838
• Species: Drosophila melanogaster
• Sequence 2: NP_009759.3
• Gene: BEM1 / 852499
• SGDID: S000000404
• Length: 551
• Species: Saccharomyces cerevisiae
• Alignment Length: 373
• Identity: 74/373 - (19%)
• Similarity: 112/373 - (30%)
• Gaps: 151/373 - (40%)

  Fly   139 HAYALFDFASGEATDLKFKKGDLILIKHRIDNNWFVGQANGQ---EGTFPINYVKV--------- 191
            :|..|:||.:.:|.:|....|:.:.|....:..||:.:..|:   .|..|:.:|.:
Yeast   159 YAIVLYDFKAEKADELTTYVGENLFICAHHNCEWFIAKPIGRLGGPGLVPVGFVSIIDIATGYAT 223

  Fly   192 ---------SVPLPMPQ----CIAMYDF------------------------------------- 206
                     ||.||..|    .||.|..
Yeast   224 GNDVIEDIKSVNLPTVQEWKSNIARYKASNISLGSVEQQQQQSITKPQNKSAKLVDGELLVKASV 288

  Fly   207 -KMGPNDEE----GCLEFKKSTVIQVMRRVDHNWAEGRIGQTIGIFPIAFVELNAAAKKLLDSGL 266
             ..|..||:    .|.|.......| ::|...::.:.:: |.:..||       |.|.||.|:|
Yeast   289 ESFGLEDEKYWFLVCCELSNGKTRQ-LKRYYQDFYDLQV-QLLDAFP-------AEAGKLRDAG- 343

  Fly   267 HTHPFCHPPKQQGQRALPPVPVIDPTVVTESSSGSSNSTPGSSNSSSTSSSNNCSPNHQISLPNT 331
                     .|..:|.:|.:|               ...|..:||.:.....:.: .:...|.|.
Yeast   344 ---------GQWSKRIMPYIP---------------GPVPYVTNSITKKRKEDLN-IYVADLVNL 383

  Fly   332 PQHVVASGSASVRFRDKGAKEKRHSLNALLGGGAP------------------------------ 366
            |.::..|             |..|||..:|..|..
Yeast   384 PDYISRS-------------EMVHSLFVVLNNGFDREFERDENQNNIKTLQENDTATFATASQTS 435

  Fly   367 --LSLLQTNRHSAEILSLPHELSRLEVSSSTALKPTSAPQTSRVLKTT 412
              .|..|.|..:.|.|.|..:||.|.:|.|   |...|..||. ||||
Yeast   436 NFASTNQDNTLTGEDLKLNKKLSDLSLSGS---KQAPAQSTSG-LKTT 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
POSH	NP_523776.1	RING	11..53	CDD:238093
		SH3	139..191	CDD:302595	14/54 (26%)
		SH3_SH3RF_2	199..251	CDD:212721	14/97 (14%)
		SH3_SH3RF_3	424..477	CDD:212717
		SH3_SH3RF_C	782..836	CDD:212719
BEM1	NP_009759.3	SH3_Bem1p_1	76..127	CDD:212811
		SH3_Bem1p_2	159..214	CDD:212812	14/54 (26%)
		PX_Bem1p	284..400	CDD:132800	31/163 (19%)
		PB1	478..549	CDD:214770	2/2 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46655
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000