DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment POSH and l(3)05822

DIOPT Version :9

Sequence 1:	NP_523776.1	Gene:	POSH / 36990	FlyBaseID:	FBgn0040294	Length:	838	Species:	Drosophila melanogaster
Sequence 2:	NP_001262702.1	Gene:	l(3)05822 / 47260	FlyBaseID:	FBgn0010877	Length:	600	Species:	Drosophila melanogaster

Alignment Length:	201	Identity:	55/201 - (27%)
Similarity:	84/201 - (41%)	Gaps:	45/201 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 GEETETQPERAK----PQPPAES-------VAPPDNQLLQLQSHQQSHQPARHKQRRFLLPHAYA 142
            |.||...|...|    |.|||.|       |.......|.|.:..|.:....      ::|:|.|
  Fly   400 GSETPPSPPMPKGPPPPPPPASSGGISLLDVINGKVDALALSNGCQGYMEEE------VVPYAVA 458

  Fly   143 LFDFASGEATDLKFKKGDLILIKHRIDNNWFVGQA-NGQEGTFPINYVKVSVPL----------- 195
            |:||...|..||.|::|:.|.:.......|..|:. :|.||.||||||.:.|||
  Fly   459 LYDFDGIEPGDLSFREGEKIYLLDHPTPEWLRGRTRSGCEGIFPINYVDIKVPLGATGGAAAAPT 523

  Fly   196 -------------PMPQCIAMYDFKMGPNDEEGCLEFKKSTVIQVMRRVDHNWAEGRIGQTIGIF 247
                         .:|..:.:|.|   |.:.||.|..:::.::.|:.|::.:|..|.:....|.|
  Fly   524 ASAAAPSPSPSQQQLPTALCLYHF---PGEVEGDLALQENELVTVLYRINEDWLYGEVAGRQGQF 585

  Fly   248 PIAFVE 253
            |..|::
  Fly   586 PANFLD 591

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
POSH	NP_523776.1	RING	11..53	CDD:238093
		SH3	139..191	CDD:302595	22/52 (42%)
		SH3_SH3RF_2	199..251	CDD:212721	13/51 (25%)
		SH3_SH3RF_3	424..477	CDD:212717
		SH3_SH3RF_C	782..836	CDD:212719
l(3)05822	NP_001262702.1	SH3	452..506	CDD:214620	21/53 (40%)
l(3)05822	NP_001262702.1	SH3	540..591	CDD:302595	14/53 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D77892at33392
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46655
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010