Protein Alignment POSH and Lasp

DIOPT Version :10

• Sequence 1: NP_523776.1
• Gene: POSH / 36990
• FlyBaseID: FBgn0040294
• Length: 838
• Species: Drosophila melanogaster
• Sequence 2: NP_730192.2
• Gene: Lasp / 39864
• FlyBaseID: FBgn0063485
• Length: 657
• Species: Drosophila melanogaster
• Alignment Length: 531
• Identity: 103/531 - (19%)
• Similarity: 156/531 - (29%)
• Gaps: 231/531 - (43%)

  Fly   481 RDQQQLMHQWKYVPQNADAQMAQVQQHPVAPDVRLNNMLSMQPPDLPP----RQQQATATTTSC- 540
            :.||||.||.:...|....|:.| |||      :..:.|..|...|||    .||..||..|..
  Fly   178 QQQQQLQHQQQQQYQQHQQQLQQ-QQH------QHQHYLQQQQQTLPPPPIQHQQYNTAAITPTY 235

  Fly   541 ------------------------SVWSKPVEALFSRKSEPKPETATASTTSSSSSGAVGLMRRL 581
                                    :.:.:| :||..::.:.:.:........:        :::.
  Fly   236 QQLQQQQQQQQQQRAQQQQLHDPYAHYQQP-QALRQQQQQQQQQQQQLLQQQA--------IKQA 291

  Fly   582 THMKTRSKSPGASLQQVPKEAISTNVE------FTTNPSAKLHPVHVRSGSCPSQLQHSQPLNET 640
            :|:...:.|   ..||:|......|.:      :....||.|...|..||:  |..|:.||
  Fly   292 SHLYPTATS---QQQQMPPPQSPANPQQQALNSYNEMRSAILQNSHHPSGN--SVDQYDQP---- 347

  Fly   641 PAAKTAAQQQQFLPKQLPSASTNSVSYGSQRVKGSKERPHLICARQSLDAATFRSMYNNAAS--- 702
                   ||||..|:|   .|||               |.|:.|:|.   .:..|:.||.||
  Fly   348 -------QQQQHQPQQ---QSTN---------------PTLVAAQQQ---QSHHSLLNNNASNGG 384

  Fly   703 ---------------------PPPPTTSVAPAV-YAGGQQQVIPGGGAQSQLHANMIIA------ 739
                                 ||....|.|..| |.|..:|.:..|...:|.|...:.|
  Fly   385 ISHSHHSNINNNGHGSQNQMLPPQMRRSAASVVAYDGNSKQQVAAGPGAAQNHLQQLYASPNYAA 449

  Fly   740 -------------------PSHRKSHSLDASHV--------LSPSSNMITEAAIKASATT----- 772
                               |:.::.|....|::        |:....::..|.  .|:||
  Fly   450 VTPSENSINVKQHASNGHMPNQQQQHVAGGSNIGKIADYDPLTDGPRVVPNAG--RSSTTLVYSS 512

  Fly   773 --------KSPYCTR-------------------------------------------------- 779
                    .|.|..|
  Fly   513 EPRGNQGGNSVYPKRIGSVSDIDPANGIYGSLTAAEQAHQQQKHQQYYQQVQMMQQQEHPPQQQQ 577

  Fly   780 -------------ESR-------FRCIVPYPPNSDIELELHLGDIIYVQRKQKNGWYKGTHARTH 824
                         :||       :|.|..|......|:....||:|:......:||..|...||.
  Fly   578 MRQQPSYSSLQEKQSRQSTAMRVYRAIYDYEAQDVDEVSFREGDVIFEVESIDSGWMTGRVERTG 642

  Fly   825 KTGLFPASFVE 835
            |||:.||::||
  Fly   643 KTGMLPANYVE 653

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
POSH	NP_523776.1	RAD18	6..>113	CDD:227719
		RING-HC_SH3RF3	8..53	CDD:438408
		SH3	139..191	CDD:473055
		SH3_SH3RF_2	199..251	CDD:212721
		SH3_SH3RF_3	424..477	CDD:212717
		SH3_SH3RF_C	782..836	CDD:212719	20/61 (33%)
Lasp	NP_730192.2	LIM_LASP	5..57	CDD:188831
		Nebulin	67..94	CDD:459977
		NEBU	97..127	CDD:128523
		SH3_Nebulin_family_C	600..654	CDD:212723	19/54 (35%)